[15] NY Islanders 3-4 DET Red Wings [4] 2021-12-05 00:00
Stadium: Little Caesars Arena
Home Manager: Jeff Blashill Away Manager: Barry Trotz
Head to Head
| NHL | 2020/02/22 01:00 | DET Red Wings v NY Islanders | W | 1-4 |
| NHL | 2020/01/15 00:00 | DET Red Wings v NY Islanders | W | 2-8 |
| NHL | 2019/12/03 00:30 | NY Islanders v DET Red Wings | W | 4-1 |
| NHL Pre-Season | 2019/09/23 23:00 | DET Red Wings v NY Islanders | W | 2-3 |
| NHL Pre-Season | 2019/09/20 23:30 | NY Islanders v DET Red Wings | W | 4-3 |
| NHL | 2019/03/16 17:00 | NY Islanders v DET Red Wings | L | 1-2 |
| NHL | 2018/12/16 00:00 | DET Red Wings v NY Islanders | W | 3-4 |
| NHL | 2018/12/09 00:00 | NY Islanders v DET Red Wings | W | 3-2 |
Home History
| NHL | 2021/12/03 00:30 | SJ Sharks v NY Islanders | L | 2-1 |
| NHL | 2021/11/27 00:30 | PIT Penguins v NY Islanders | L | 1-0 |
| NHL | 2021/11/25 00:30 | NY Rangers v NY Islanders | L | 4-1 |
| NHL | 2021/11/22 00:30 | TOR Maple Leafs v NY Islanders | L | 3-0 |
| NHL | 2021/11/21 00:00 | CAL Flames v NY Islanders | L | 5-2 |
| NHL | 2021/11/17 00:00 | NY Islanders v FLA Panthers | L | 1-6 |
| NHL | 2021/11/16 00:00 | NY Islanders v TB Lightning | L | 1-4 |
| NHL | 2021/11/12 00:00 | NY Islanders v NJ Devils | L | 0-4 |
Away History
| NHL | 2021/12/02 00:30 | SEA Kraken v DET Red Wings | W | 3-4 |
| NHL | 2021/12/01 00:00 | DET Red Wings v BOS Bruins | W | 2-1 |
| NHL | 2021/11/28 00:00 | BUF Sabres v DET Red Wings | W | 2-3 |
| NHL | 2021/11/25 00:30 | STL Blues v DET Red Wings | W | 2-4 |
| NHL | 2021/11/21 01:00 | DET Red Wings v ARZ Coyotes | L | 1-2 |
| NHL | 2021/11/19 03:00 | DET Red Wings v VGS Golden Knights | L | 2-5 |
| NHL | 2021/11/17 01:30 | DET Red Wings v DAL Stars | L | 2-5 |
| NHL | 2021/11/16 00:00 | DET Red Wings v CLB Blue Jackets | L | 3-5 |