[14] NY Islanders 5-3 OTT Senators [7] 2021-12-08 00:00
Stadium: Canadian Tire Centre
Home Manager: Away Manager: Barry Trotz
Head to Head
| NHL | 2020/03/06 00:30 | NY Islanders v OTT Senators | L | 3-4 |
| NHL | 2019/11/06 00:00 | OTT Senators v NY Islanders | W | 1-4 |
| NHL | 2019/10/25 23:30 | NY Islanders v OTT Senators | W | 4-2 |
| NHL | 2019/03/08 00:30 | NY Islanders v OTT Senators | W | 4-2 |
| NHL | 2019/03/06 00:00 | OTT Senators v NY Islanders | W | 4-5 |
| NHL | 2018/12/29 00:00 | OTT Senators v NY Islanders | W | 3-6 |
| NHL | 2018/03/27 23:30 | NY Islanders v OTT Senators | W | 4-3 |
| NHL | 2017/12/02 00:00 | OTT Senators v NY Islanders | L | 6-5 |
Home History
| NHL | 2021/12/06 00:30 | CHI Blackhawks v NY Islanders | L | 3-2 |
| NHL | 2021/12/05 00:00 | NY Islanders v DET Red Wings | L | 3-4 |
| NHL | 2021/12/03 00:30 | SJ Sharks v NY Islanders | L | 2-1 |
| NHL | 2021/11/27 00:30 | PIT Penguins v NY Islanders | L | 1-0 |
| NHL | 2021/11/25 00:30 | NY Rangers v NY Islanders | L | 4-1 |
| NHL | 2021/11/22 00:30 | TOR Maple Leafs v NY Islanders | L | 3-0 |
| NHL | 2021/11/21 00:00 | CAL Flames v NY Islanders | L | 5-2 |
| NHL | 2021/11/17 00:00 | NY Islanders v FLA Panthers | L | 1-6 |
Away History
| NHL | 2021/12/07 00:00 | OTT Senators v NJ Devils | W | 3-2 |
| NHL | 2021/12/05 00:00 | COL Avalanche v OTT Senators | D | 5-5 |
| NHL | 2021/12/03 00:00 | OTT Senators v CAR Hurricanes | W | 3-2 |
| NHL | 2021/12/02 00:30 | VAN Canucks v OTT Senators | L | 6-2 |
| NHL | 2021/11/28 00:00 | OTT Senators v LA Kings | L | 2-4 |
| NHL | 2021/11/26 21:00 | OTT Senators v ANA Ducks | L | 0-4 |
| NHL | 2021/11/25 03:30 | OTT Senators v SJ Sharks | L | 3-6 |
| NHL | 2021/11/23 01:30 | OTT Senators v COL Avalanche | L | 5-7 |