Head to Head
| NHL Pre-Season | 2021/09/26 00:00 | MIN Wild v STL Blues | W | 2-6 |
| NHL | 2021/05/14 00:00 | MIN Wild v STL Blues | W | 3-7 |
| NHL | 2021/05/13 01:00 | MIN Wild v STL Blues | W | 0-4 |
| NHL | 2021/05/02 00:00 | STL Blues v MIN Wild | L | 3-4 |
| NHL | 2021/04/30 00:00 | STL Blues v MIN Wild | W | 5-4 |
| NHL | 2021/04/28 23:00 | STL Blues v MIN Wild | W | 4-3 |
| NHL | 2021/04/11 00:00 | MIN Wild v STL Blues | W | 2-3 |
| NHL | 2021/04/10 00:00 | MIN Wild v STL Blues | W | 1-9 |
Home History
| NHL Pre-Season | 2021/10/06 00:00 | STL Blues v DAL Stars | L | 1-3 |
| NHL Pre-Season | 2021/10/03 00:00 | CHI Blackhawks v STL Blues | L | 5-1 |
| NHL Pre-Season | 2021/10/02 00:30 | STL Blues v CHI Blackhawks | W | 6-3 |
| NHL Pre-Season | 2021/09/29 23:00 | STL Blues v CLB Blue Jackets | L | 2-5 |
| NHL Pre-Season | 2021/09/28 00:00 | DAL Stars v STL Blues | W | 1-2 |
| NHL Pre-Season | 2021/09/26 00:00 | MIN Wild v STL Blues | W | 2-6 |
| NHL | 2021/05/23 21:00 | COL Avalanche v STL Blues | L | 5-2 |
| NHL | 2021/05/22 01:30 | COL Avalanche v STL Blues | L | 5-1 |
Away History
| NHL Pre-Season | 2021/10/05 00:00 | COL Avalanche v MIN Wild | W | 1-3 |
| NHL Pre-Season | 2021/10/01 01:00 | MIN Wild v COL Avalanche | L | 4-6 |
| NHL Pre-Season | 2021/09/26 00:00 | MIN Wild v STL Blues | L | 2-6 |
| NHL | 2021/05/29 01:00 | MIN Wild v VGS Golden Knights | L | 2-6 |
| NHL | 2021/05/27 01:00 | VGS Golden Knights v MIN Wild | W | 0-3 |
| NHL | 2021/05/25 02:30 | MIN Wild v VGS Golden Knights | W | 4-2 |
| NHL | 2021/05/23 00:00 | VGS Golden Knights v MIN Wild | L | 4-0 |
| NHL | 2021/05/21 01:30 | VGS Golden Knights v MIN Wild | L | 5-2 |