| Guatemala Liga Nacional Women | 2021/08/16 00:00 | Deportivo Mixco Women v Santa Lucia Cotzumalguapa Women | L | 2-1 |
| Guatemala Liga Nacional Women | 2021/09/05 17:00 | Santa Lucia Cotzumalguapa Women v Pares Women | W | 3-2 |
| Guatemala Liga Nacional Women | 2021/08/22 16:00 | Santa Lucia Cotzumalguapa Women v Antigua GFC Women | L | 1-2 |
| Guatemala Liga Nacional Women | 2021/08/16 00:00 | Deportivo Mixco Women v Santa Lucia Cotzumalguapa Women | L | 2-1 |
| Guatemala Liga Nacional Women | 2021/09/15 17:00 | Antigua GFC Women v Deportivo Mixco Women | L | 1-0 |
| Guatemala Liga Nacional Women | 2021/09/12 15:30 | Pares Women v Deportivo Mixco Women | W | 0-2 |
| Guatemala Liga Nacional Women | 2021/08/23 00:00 | Deportivo Mixco Women v CSD Barcena FF Women | W | 2-1 |
| Guatemala Liga Nacional Women | 2021/08/16 00:00 | Deportivo Mixco Women v Santa Lucia Cotzumalguapa Women | W | 2-1 |
| Women’s Friendly | 2021/08/02 00:00 | Deportivo Mixco Women v CSD Concepcion Women | W | 1-0 |
| Guatemala Liga Nacional Women | 2021/05/03 00:00 | Deportivo Mixco Women v Antigua GFC Women | D | 2-2 |
| Guatemala Liga Nacional Women | 2021/04/29 21:30 | Deportivo Amatitlan Women v Deportivo Mixco Women | L | 9-1 |
| Guatemala Liga Nacional Women | 2021/04/12 00:00 | Deportivo Mixco Women v CSD Municipal Women | L | 0-2 |