[11] NJ Devils 2-4 NY Islanders [14] 2021-12-12 00:30
Stadium: UBS Arena
Home Manager: Barry Trotz Away Manager: Lindy Ruff
Head to Head
| NHL | 2021/11/12 00:00 | NY Islanders v NJ Devils | W | 0-4 |
| NHL Pre-Season | 2021/10/02 18:00 | NJ Devils v NY Islanders | W | 2-1 |
| NHL | 2021/05/08 23:00 | NJ Devils v NY Islanders | L | 1-5 |
| NHL | 2021/05/06 23:00 | NJ Devils v NY Islanders | W | 2-1 |
| NHL | 2021/03/14 21:00 | NY Islanders v NJ Devils | L | 3-2 |
| NHL | 2021/03/14 00:00 | NY Islanders v NJ Devils | L | 3-2 |
| NHL | 2021/03/12 00:00 | NJ Devils v NY Islanders | L | 3-5 |
| NHL | 2021/03/03 00:00 | NY Islanders v NJ Devils | L | 2-1 |
Home History
| NHL | 2021/12/11 00:30 | NAS Predators v NJ Devils | L | 3-2 |
| NHL | 2021/12/09 00:00 | PHI Flyers v NJ Devils | W | 0-3 |
| NHL | 2021/12/07 00:00 | OTT Senators v NJ Devils | L | 3-2 |
| NHL | 2021/12/04 01:00 | NJ Devils v WIN Jets | L | 4-8 |
| NHL | 2021/12/03 01:00 | NJ Devils v MIN Wild | L | 2-5 |
| NHL | 2021/12/01 00:00 | SJ Sharks v NJ Devils | L | 5-2 |
| NHL | 2021/11/29 00:00 | PHI Flyers v NJ Devils | W | 2-5 |
| NHL | 2021/11/26 23:00 | NJ Devils v NAS Predators | L | 2-4 |
Away History
| NHL | 2021/12/10 00:30 | NAS Predators v NY Islanders | L | 4-3 |
| NHL | 2021/12/08 00:00 | NY Islanders v OTT Senators | W | 5-3 |
| NHL | 2021/12/06 00:30 | CHI Blackhawks v NY Islanders | L | 3-2 |
| NHL | 2021/12/05 00:00 | NY Islanders v DET Red Wings | L | 3-4 |
| NHL | 2021/12/03 00:30 | SJ Sharks v NY Islanders | L | 2-1 |
| NHL | 2021/11/27 00:30 | PIT Penguins v NY Islanders | L | 1-0 |
| NHL | 2021/11/25 00:30 | NY Rangers v NY Islanders | L | 4-1 |
| NHL | 2021/11/22 00:30 | TOR Maple Leafs v NY Islanders | L | 3-0 |