| Bolivia Reserve League | 2021/05/01 19:30 | Guabira Reserves v Real Santa Cruz Reserves | W | 0-1 |
| Bolivia Reserve League | 2021/09/10 13:20 | Real Tomayapo Reserves v Real Santa Cruz Reserves | W | 0-1 |
| Bolivia Reserve League | 2021/08/16 16:00 | The Strongest Reserves v Real Santa Cruz Reserves | L | 6-0 |
| Bolivia Reserve League | 2021/07/02 14:46 | Atletico Palmaflor Vinto Reserves v Real Santa Cruz Reserves | L | 3-0 |
| Bolivia Reserve League | 2021/06/26 15:43 | Real Santa Cruz Reserves v Jorge Wilstermann Reserves | D | 1-1 |
| Bolivia Reserve League | 2021/05/01 19:30 | Guabira Reserves v Real Santa Cruz Reserves | W | 0-1 |
| Bolivia Reserve League | 2021/08/23 15:00 | Bolivar Reserves v Guabira Reserves | L | 2-0 |
| Bolivia Reserve League | 2021/08/16 15:30 | Independiente Petrolero Reserves v Guabira Reserves | L | 5-1 |
| Bolivia Reserve League | 2021/07/10 13:00 | Guabira Reserves v Oriente Petrolero Reserves | L | 1-4 |
| Bolivia Reserve League | 2021/07/03 14:30 | Guabira Reserves v Bolivar Reserves | D | 3-3 |
| Bolivia Reserve League | 2021/06/26 14:00 | Blooming Reserves v Guabira Reserves | D | 1-1 |
| Bolivia Reserve League | 2021/05/01 19:30 | Guabira Reserves v Real Santa Cruz Reserves | L | 0-1 |