| Portugal Campeonato Nacional | 2021/09/19 14:00 | Serpa v Imortal DC | W | 0-1 |
| Portugal Campeonato Nacional | 2021/12/12 15:00 | FC Barreirense v Imortal DC | D | 0-0 |
| Portugal Campeonato Nacional | 2021/12/06 20:30 | Imortal DC v Esperanca Lagos | D | 0-0 |
| Portugal Campeonato Nacional | 2021/11/28 15:00 | Imortal DC v Olhanense | L | 1-2 |
| Portugal Campeonato Nacional | 2021/11/07 15:00 | GUS Montemor v Imortal DC | W | 0-2 |
| Portugal Campeonato Nacional | 2021/10/31 15:00 | Imortal DC v Moncarapachense | D | 1-1 |
| Portugal Campeonato Nacional | 2021/10/24 14:00 | CD Pinhalnovense v Imortal DC | L | 3-0 |
| Portugal Campeonato Nacional | 2021/10/03 14:00 | Imortal DC v Juventude Evora | D | 1-1 |
| Portugal Cup | 2021/09/25 14:00 | Imortal DC v Vilafranquense | L | 0-2 |
| Portugal Campeonato Nacional | 2021/12/19 15:00 | Serpa v GUS Montemor | W | 2-1 |
| Portugal Campeonato Nacional | 2021/12/12 15:00 | Serpa v Moncarapachense | L | 1-5 |
| Portugal Campeonato Nacional | 2021/12/05 15:00 | CD Pinhalnovense v Serpa | L | 4-1 |
| Portugal Campeonato Nacional | 2021/11/28 15:00 | Serpa v Juventude Evora | L | 0-3 |
| Portugal Cup | 2021/11/21 11:00 | Serpa v Estoril | L | 0-5 |
| Portugal Campeonato Nacional | 2021/11/07 15:00 | Serpa v Olhanense | L | 0-3 |
| Portugal Campeonato Nacional | 2021/10/31 15:00 | Louletano DC v Serpa | L | 6-0 |
| Portugal Campeonato Nacional | 2021/10/24 14:00 | Serpa v FC Barreirense | W | 1-0 |