[11] St Lucia 0-0 Sliema Wanderers [12] 2021-10-24 13:00
Stadium: Luxol Sports Ground Round: 7
Home Manager: Oliver Spiteri Away Manager: Andrea Pisanu
Head to Head
| Malta Premier League | 2021/01/29 20:00 | Santa Lucia FC v Sliema Wanderers | L | 0-1 |
| Malta Premier League | 2020/10/01 19:15 | Sliema Wanderers v Santa Lucia FC | L | 3-1 |
| Malta FA Trophy | 2019/12/01 13:00 | Sliema Wanderers v Santa Lucia FC | W | 0-2 |
| Malta Premier League | 2019/11/23 13:00 | Santa Lucia FC v Sliema Wanderers | L | 0-4 |
Home History
| Malta Premier League | 2021/10/17 17:00 | Santa Lucia FC v Mosta FC | D | 2-2 |
| Malta Premier League | 2021/09/25 19:00 | Hibernians v Santa Lucia FC | D | 1-1 |
| Malta Premier League | 2021/09/18 15:00 | Santa Lucia FC v Sirens | L | 1-3 |
| Malta Premier League | 2021/09/12 19:00 | Gudja United v Santa Lucia FC | D | 2-2 |
| Malta Premier League | 2021/08/22 17:00 | Santa Lucia FC v Gzira United | D | 1-1 |
| Malta Premier League | 2021/08/14 18:00 | Floriana v Santa Lucia FC | D | 2-2 |
| Europe Friendlies | 2021/07/16 18:00 | Hamrun Spartans v Santa Lucia FC | D | 0-0 |
| Malta Premier League | 2021/03/06 17:00 | Lija Athletic v Santa Lucia FC | L | 3-1 |
Away History
| Malta Premier League | 2021/10/17 13:00 | Sliema Wanderers v Hibernians | L | 0-3 |
| Malta Premier League | 2021/09/26 17:00 | Sirens v Sliema Wanderers | D | 2-2 |
| Malta Premier League | 2021/09/19 17:00 | Sliema Wanderers v Gudja United | L | 2-3 |
| Malta Premier League | 2021/09/11 19:00 | Gzira United v Sliema Wanderers | D | 1-1 |
| Malta Premier League | 2021/08/20 17:00 | Sliema Wanderers v Floriana | D | 0-0 |
| Malta Premier League | 2021/08/12 18:00 | Balzan FC v Sliema Wanderers | L | 1-0 |
| Malta Premier League | 2021/03/06 17:00 | Sliema Wanderers v Gzira United | W | 2-0 |
| Malta Premier League | 2021/02/28 13:00 | Balzan FC v Sliema Wanderers | L | 5-1 |