Northwestern 17-41 Duke 2017-09-09 16:00
Stadium: Brooks Field at Wallace Wade Stadium Round: 1
Head to Head
| NCAAF | 2016/09/18 00:00 | Northwestern v Duke | W | 24-13 |
| NCAAF | 2015/09/19 16:30 | Duke v Northwestern | W | 10-19 |
| NCAAF | 2008/09/06 12:00 | Duke v Northwestern | W | 20-24 |
| NCAAF | 2007/09/15 12:00 | Northwestern v Duke | L | 14-20 |
| NCAAF | 2003/09/20 12:00 | Duke v Northwestern | W | 10-28 |
| NCAAF | 2002/09/14 12:00 | Northwestern v Duke | W | 26-21 |
| NCAAF | 2001/09/22 12:00 | Duke v Northwestern | W | 7-44 |
| NCAAF | 2000/09/09 12:00 | Northwestern v Duke | W | 38-5 |
Home History
| NCAAF | 2017/09/02 19:30 | Nevada v Northwestern | W | 20-31 |
| NCAAF | 2016/12/28 19:00 | Northwestern v Pittsburgh | W | 31-24 |
| NCAAF | 2016/11/26 17:00 | Illinois v Northwestern | W | 21-42 |
| NCAAF | 2016/11/19 20:30 | Northwestern v Minnesota | L | 12-29 |
| NCAAF | 2016/11/12 17:00 | Northwestern v Purdue | W | 45-17 |
| NCAAF | 2016/11/05 16:00 | Wisconsin v Northwestern | L | 21-7 |
| NCAAF | 2016/10/29 19:30 | Northwestern v Ohio State | L | 20-24 |
| NCAAF | 2016/10/22 16:00 | Indiana v Northwestern | W | 14-24 |
Away History
| NCAAF | 2017/09/02 22:00 | North Carolina Central v Duke | W | 7-60 |
| NCAAF | 2016/11/26 20:30 | Duke v Miami Florida | L | 21-40 |
| NCAAF | 2016/11/19 20:00 | Duke v Pittsburgh | L | 14-56 |
| NCAAF | 2016/11/11 00:30 | North Carolina v Duke | W | 27-28 |
| NCAAF | 2016/11/05 19:30 | Virginia Tech v Duke | L | 24-21 |
| NCAAF | 2016/10/29 16:00 | Duke v Georgia Tech | L | 35-38 |
| NCAAF | 2016/10/14 23:00 | Duke v Louisville | L | 14-24 |
| NCAAF | 2016/10/08 19:30 | Army v Duke | W | 6-13 |