Louisville 47-35 North Carolina 2017-09-09 16:00
Stadium: Kenan Stadium Round: 1
Head to Head
| NCAAF | 2012/09/15 12:00 | Louisville v North Carolina | W | 39-34 |
| NCAAF | 2011/10/08 12:00 | North Carolina v Louisville | L | 14-7 |
| NCAAF | 2005/10/08 12:00 | Louisville v North Carolina | W | 69-14 |
| NCAAF | 2004/09/25 12:00 | North Carolina v Louisville | W | 0-34 |
Home History
| NCAAF | 2017/09/02 23:36 | Louisville v Purdue | W | 35-28 |
| NCAAF | 2017/09/02 23:30 | Purdue v Louisville | W | 28-35 |
| NCAAF | 2016/12/31 16:00 | LSU v Louisville | L | 29-9 |
| NCAAF | 2016/11/26 17:00 | Kentucky v Louisville | L | 41-38 |
| NCAAF | 2016/11/18 01:00 | Louisville v Houston | L | 10-36 |
| NCAAF | 2016/11/13 00:00 | Wake Forest v Louisville | W | 12-44 |
| NCAAF | 2016/11/05 16:00 | Louisville v Boston College | W | 52-7 |
| NCAAF | 2016/10/29 16:00 | Louisville v Virginia | W | 32-25 |
Away History
| NCAAF | 2017/09/02 16:20 | California v North Carolina | L | 35-30 |
| NCAAF | 2016/12/30 19:00 | North Carolina v Stanford | L | 23-25 |
| NCAAF | 2016/11/25 17:00 | NC State v North Carolina | L | 28-21 |
| NCAAF | 2016/11/19 20:30 | The Citadel v North Carolina | W | 7-41 |
| NCAAF | 2016/11/11 00:30 | North Carolina v Duke | L | 27-28 |
| NCAAF | 2016/11/05 16:30 | Georgia Tech v North Carolina | W | 20-48 |
| NCAAF | 2016/10/22 19:00 | North Carolina v Virginia | W | 35-14 |
| NCAAF | 2016/10/15 19:30 | North Carolina v Miami Florida | W | 20-13 |