| Panama Liga Prom | 2021/04/10 20:00 | San Francisco Reserves v Herrera FC Reserves | L | 3-1 |
| Panama Liga Prom | 2021/10/01 23:00 | SD Atletico Nacional v Herrera FC Reserves | D | 0-0 |
| Panama Liga Prom | 2021/09/26 22:00 | Aguilas de la U v Herrera FC Reserves | L | 2-0 |
| Panama Liga Prom | 2021/09/18 22:00 | Herrera FC Reserves v Udelas FC | W | 1-0 |
| Panama Liga Prom | 2021/09/11 00:00 | CA Independiente de la Chorrera Reserves v Herrera FC Reserves | L | 2-1 |
| Panama Liga Prom | 2021/08/28 22:00 | Mario Mendez FC v Herrera FC Reserves | L | 3-0 |
| Panama Liga Prom | 2021/08/21 20:43 | Veraguas CD Reserves v Herrera FC Reserves | D | 1-1 |
| Panama Liga Prom | 2021/08/20 21:00 | Veraguas CD Reserves v Herrera FC Reserves | D | 1-1 |
| Panama Liga Prom | 2021/08/13 23:00 | Herrera FC Reserves v Atletico Chiriqui B | D | 0-0 |
| Panama Liga Prom | 2021/10/03 22:00 | Atletico Chiriqui B v San Francisco Reserves | L | 2-1 |
| Panama Liga Prom | 2021/09/24 20:00 | CD Universitario Reserves v San Francisco Reserves | W | 2-4 |
| Panama Liga Prom | 2021/09/19 00:00 | San Francisco Reserves v Mario Mendez FC | L | 0-1 |
| Panama Liga Prom | 2021/09/10 21:00 | Veraguas CD Reserves v San Francisco Reserves | W | 0-1 |
| Panama Liga Prom | 2021/09/04 00:00 | SD Panama Oeste v San Francisco Reserves | L | 2-1 |
| Panama Liga Prom | 2021/08/28 22:00 | San Francisco Reserves v CA Independiente de la Chorrera Reserves | D | 0-0 |
| Panama Liga Prom | 2021/08/19 20:00 | Udelas FC v San Francisco Reserves | W | 2-3 |
| Panama Liga Prom | 2021/08/13 20:00 | San Francisco Reserves v SD Atletico Nacional | L | 1-2 |