[24] John Isner 6-3,6-4 Yoshihito Nishioka [75] 2021-10-11 03:30
Stadium: Stadium 2 Round: 24 Ground: Hardcourt outdoor
Head to Head
| Wimbledon | 2021/06/30 10:00 | Yoshihito Nishioka v John Isner | 7-6,2-6,6-3,6-7,6-4 |
| ATP Memphis | 2017/02/16 01:30 | Yoshihito Nishioka v John Isner | 6-4,3-6,4-6 |
Home History
| Laver Cup | 2021/09/25 18:50 | Alexander Zverev v John Isner | 7-6,6-7,10-5 |
| US Open | 2021/08/30 17:35 | John Isner v Brandon Nakashima | 6-7,6-7,3-6 |
| ATP Cincinnati | 2021/08/19 16:05 | John Isner v Benoit Paire | 6-7,7-6,1-6 |
| ATP Cincinnati | 2021/08/18 19:35 | Jannik Sinner v John Isner | 7-5,6-7,4-6 |
| ATP Cincinnati | 2021/08/17 17:55 | John Isner v Cameron Norrie | 4-6,7-6,6-4 |
| ATP Toronto | 2021/08/15 00:00 | Daniil Medvedev v John Isner | 6-2,6-2 |
| ATP Toronto | 2021/08/14 01:35 | John Isner v Gael Monfils | 7-6,6-4 |
| ATP Toronto | 2021/08/12 16:35 | Andrey Rublev v John Isner | 5-7,6-7 |
Away History
| ATP Indian Wells | 2021/10/08 18:00 | Federico Delbonis v Yoshihito Nishioka | 3-6,6-3,6-7 |
| US Open | 2021/08/31 19:50 | Yoshihito Nishioka v Jack Sock | 7-6,2-6,4-6,2-6 |
| ATP Cincinnati | 2021/08/16 20:25 | Yoshihito Nishioka v Lloyd Harris | 3-6,4-6 |
| ATP Cincinnati | 2021/08/15 15:00 | Yoshihito Nishioka v Ricardas Berankis | 6-7,7-5,6-2 |
| ATP Cincinnati | 2021/08/14 14:00 | Yoshihito Nishioka v Egor Gerasimov | 6-2,6-3 |
| ATP Toronto | 2021/08/10 18:00 | Yoshihito Nishioka v Frances Tiafoe | 4-6,3-6 |
| ATP Toronto | 2021/08/08 17:35 | Yoshihito Nishioka v Feliciano Lopez | 7-5,7-6 |
| ATP Toronto | 2021/08/07 22:10 | Yoshihito Nishioka v Michael Mmoh | 7-6,6-2 |