Head to Head
| MLB | 2021/10/11 00:07 | HOU Astros v CHI White Sox | L | 6-12 |
| MLB | 2021/10/08 18:07 | CHI White Sox v HOU Astros | W | 4-9 |
| MLB | 2021/10/07 20:07 | CHI White Sox v HOU Astros | W | 1-6 |
| MLB | 2021/07/18 18:10 | HOU Astros v CHI White Sox | L | 0-4 |
| MLB | 2021/07/17 23:15 | HOU Astros v CHI White Sox | L | 1-10 |
| MLB | 2021/07/17 00:10 | HOU Astros v CHI White Sox | W | 7-1 |
| MLB | 2021/06/20 18:10 | CHI White Sox v HOU Astros | W | 2-8 |
| MLB | 2021/06/19 23:15 | CHI White Sox v HOU Astros | W | 3-7 |
Home History
| MLB | 2021/10/11 00:07 | HOU Astros v CHI White Sox | L | 6-12 |
| MLB | 2021/10/08 18:07 | CHI White Sox v HOU Astros | W | 4-9 |
| MLB | 2021/10/07 20:07 | CHI White Sox v HOU Astros | W | 1-6 |
| MLB | 2021/10/03 19:10 | OAK Athletics v HOU Astros | W | 6-7 |
| MLB | 2021/10/02 23:10 | OAK Athletics v HOU Astros | W | 4-10 |
| MLB | 2021/10/02 00:10 | OAK Athletics v HOU Astros | L | 8-6 |
| MLB | 2021/09/30 23:10 | TB Rays v HOU Astros | W | 2-3 |
| MLB | 2021/09/30 00:10 | TB Rays v HOU Astros | L | 7-0 |
Away History
| MLB | 2021/10/11 00:07 | HOU Astros v CHI White Sox | W | 6-12 |
| MLB | 2021/10/08 18:07 | CHI White Sox v HOU Astros | L | 4-9 |
| MLB | 2021/10/07 20:07 | CHI White Sox v HOU Astros | L | 1-6 |
| MLB | 2021/10/03 19:10 | DET Tigers v CHI White Sox | L | 5-2 |
| MLB | 2021/10/02 23:10 | DET Tigers v CHI White Sox | W | 4-5 |
| MLB | 2021/10/02 00:10 | DET Tigers v CHI White Sox | W | 1-8 |
| MLB | 2021/09/30 00:10 | CIN Reds v CHI White Sox | W | 1-6 |
| MLB | 2021/09/29 00:10 | CIN Reds v CHI White Sox | W | 1-7 |