Head to Head
| Ghana Premier League | 2022/01/12 15:00 | Medeama SC v Hearts of Oak | L | 1-0 |
| Ghana FA Cup | 2021/08/01 18:00 | Hearts of Oak v Medeama SC | W | 3-0 |
| Ghana Premier League | 2021/06/13 18:00 | Hearts of Oak v Medeama SC | W | 2-0 |
| Ghana Premier League | 2021/02/04 15:00 | Medeama SC v Hearts of Oak | L | 1-0 |
| Ghana Premier League | 2020/01/05 15:00 | Medeama SC v Hearts of Oak | L | 3-0 |
| Ghana Premier League | 2018/06/03 15:00 | Hearts of Oak v Medeama SC | D | 1-1 |
| Ghana Premier League | 2017/10/15 15:00 | Medeama SC v Hearts of Oak | L | 1-0 |
| Ghana Premier League | 2017/02/19 15:00 | Hearts of Oak v Medeama SC | D | 0-0 |
Home History
| Ghana Premier League | 2022/03/30 15:00 | Berekum Chelsea v Hearts of Oak | D | 0-0 |
| Ghana FA Cup | 2022/03/27 18:30 | Hearts of Oak v Elmina Sharks | W | 10-9 |
| Ghana Premier League | 2022/03/20 18:30 | Hearts of Oak v Ashanti Gold | W | 2-1 |
| Ghana Premier League | 2022/03/13 15:00 | Aduana Stars v Hearts of Oak | L | 1-0 |
| Ghana Premier League | 2022/03/09 15:00 | Hearts of Oak v WAFA | W | 2-1 |
| Ghana Premier League | 2022/02/26 15:00 | Legon Cities FC v Hearts of Oak | D | 1-1 |
| Ghana Premier League | 2022/02/20 15:00 | Hearts of Oak v Asante Kotoko | D | 0-0 |
| Ghana Premier League | 2022/02/13 15:00 | Real Tamale United v Hearts of Oak | D | 0-0 |
Away History
| Ghana Premier League | 2022/03/30 15:00 | Medeama SC v King Faisal | W | 1-0 |
| Ghana Premier League | 2022/03/18 15:00 | Karela United FC v Medeama SC | D | 1-1 |
| Ghana Premier League | 2022/03/13 15:00 | Medeama SC v Eleven Wonders | W | 1-0 |
| Ghana Premier League | 2022/03/06 15:00 | Bibiani Gold Stars v Medeama SC | L | 1-0 |
| Ghana Premier League | 2022/02/27 15:00 | Medeama SC v Bechem FC | W | 1-0 |
| Ghana Premier League | 2022/02/14 10:00 | Medeama SC v Dreams | L | 0-1 |
| Ghana Premier League | 2022/02/05 15:00 | Accra Lions FC v Medeama SC | L | 1-0 |
| Ghana Premier League | 2022/01/30 15:00 | Medeama SC v Elmina Sharks | W | 1-0 |