| Colombia Regional League | 2021/10/11 16:00 | Sellos Colombianos v Estudiantes de Medellin | L | 2-1 |
| Colombia Regional League | 2021/10/01 17:00 | FC Leones Reserves v Estudiantes de Medellin | L | 2-0 |
| Colombia Primera C | 2021/09/29 14:14 | Halcones de Sabaneta v Estudiantes de Medellin | W | 1-6 |
| Colombia Regional League | 2021/08/30 16:10 | Estudiantes de Medellin v Independiente Sabaneta | W | 3-2 |
| Colombia Regional League | 2021/08/22 19:15 | CFD La Nororiental v Estudiantes de Medellin | L | 1-0 |
| Colombia Regional League | 2021/08/08 19:20 | Estudiantes de Medellin v Inder Girardota | W | 1-0 |
| Colombia Regional League | 2021/07/31 21:08 | Sol de Oriente v Estudiantes de Medellin | W | 0-1 |
| Colombia Regional League | 2021/07/17 19:20 | Estudiantes de Medellin v Envigado FC Reserves | L | 0-3 |
| Colombia Regional League | 2021/08/21 19:00 | CD Gallegol v Universidad de Antioquia | D | 1-1 |
| Colombia Regional League | 2021/08/07 01:00 | Politecnico J.I.C. v CD Gallegol | W | 1-3 |
| Colombia Regional League | 2021/07/18 19:21 | CD Gallegol v Real Santuario | W | 3-2 |
| Colombia Regional League | 2021/07/04 19:16 | CD Gallegol v Aguilas Doradas Reserves | L | 0-2 |
| Colombia Regional League | 2021/06/26 14:15 | Sellos Colombianos v CD Gallegol | L | 3-2 |
| Colombia Regional League | 2021/06/19 19:17 | CD Gallegol v Independiente Sabaneta | L | 2-3 |