| Colombia Regional League | 2021/10/16 17:22 | Estudiantes de Medellin v CD Gallegol | W | 3-0 |
| Colombia Regional League | 2021/10/11 16:00 | Sellos Colombianos v Estudiantes de Medellin | L | 2-1 |
| Colombia Regional League | 2021/10/01 17:00 | FC Leones Reserves v Estudiantes de Medellin | L | 2-0 |
| Colombia Primera C | 2021/09/29 14:14 | Halcones de Sabaneta v Estudiantes de Medellin | W | 1-6 |
| Colombia Regional League | 2021/08/30 16:10 | Estudiantes de Medellin v Independiente Sabaneta | W | 3-2 |
| Colombia Regional League | 2021/08/22 19:15 | CFD La Nororiental v Estudiantes de Medellin | L | 1-0 |
| Colombia Regional League | 2021/08/08 19:20 | Estudiantes de Medellin v Inder Girardota | W | 1-0 |
| Colombia Regional League | 2021/07/31 21:08 | Sol de Oriente v Estudiantes de Medellin | W | 0-1 |
| Colombia Regional League | 2021/09/21 17:00 | Politecnico J.I.C. v Total Soccer FC | L | 3-5 |
| Colombia Regional League | 2021/09/06 17:13 | Politecnico J.I.C. v Universidad de Antioquia | D | 1-1 |
| Colombia Regional League | 2021/08/28 01:06 | Politecnico J.I.C. v Real Santuario | W | 2-1 |
| Colombia Primera C | 2021/08/26 17:00 | Politecnico J.I.C. v Real Santuario | W | 2-1 |
| Colombia Primera C | 2021/08/19 17:00 | Antioquia FC v Politecnico J.I.C. | W | 1-4 |
| Colombia Regional League | 2021/08/07 01:00 | Politecnico J.I.C. v CD Gallegol | L | 1-3 |
| Colombia Regional League | 2021/07/15 15:00 | Politecnico J.I.C. v Aguilas Doradas Reserves | D | 0-0 |
| Colombia Regional League | 2021/07/02 17:19 | Politecnico J.I.C. v Independiente Sabaneta | D | 0-0 |