[6] Castres 18-20 Harlequins [6] 2021-12-12 17:30
Stadium: Stade Pierre-Fabre Round: 1
Referee: Nika Amashukeli
Head to Head
| European Rugby Champions Cup | 2015/01/24 13:00 | Castres v Harlequins | L | 19-47 |
| European Rugby Champions Cup | 2014/10/17 18:45 | Harlequins v Castres | L | 25-9 |
Home History
| French Rugby Championship | 2021/12/04 14:00 | Castres v Racing Metro | W | 25-3 |
| French Rugby Championship | 2021/11/27 14:00 | Montpellier v Castres | L | 25-24 |
| French Rugby Championship | 2021/11/06 13:45 | Lyon v Castres | L | 30-23 |
| French Rugby Championship | 2021/10/30 13:00 | Castres v Brive | W | 23-22 |
| French Rugby Championship | 2021/10/23 19:00 | Toulouse v Castres | L | 41-0 |
| French Rugby Championship | 2021/10/16 13:00 | Castres v Biarritz | W | 38-20 |
| French Rugby Championship | 2021/10/09 13:00 | La Rochelle v Castres | L | 29-10 |
| French Rugby Championship | 2021/10/02 19:05 | Castres v Toulon | W | 27-16 |
Away History
| Premiership Rugby | 2021/12/05 15:00 | Leicester v Harlequins | L | 16-14 |
| Premiership Rugby | 2021/11/27 15:00 | Harlequins v London Irish | L | 19-22 |
| Premiership Rugby Cup | 2021/11/19 19:45 | Harlequins v Northampton | W | 26-25 |
| Premiership Rugby Cup | 2021/11/13 14:30 | Saracens v Harlequins | L | 28-21 |
| Premiership Rugby | 2021/11/07 16:30 | Wasps v Harlequins | W | 16-26 |
| Premiership Rugby | 2021/10/31 15:00 | Harlequins v Saracens | L | 22-29 |
| Premiership Rugby | 2021/10/23 14:00 | Harlequins v Bath | W | 31-17 |
| Premiership Rugby | 2021/10/15 18:45 | Sale Sharks v Harlequins | L | 28-22 |