[13] Jannik Sinner 7-5,6-2 Lorenzo Musetti [69] 2021-10-20 16:20
Stadium: Centre Court Round: 26 Ground: Hardcourt indoor
Home History
| ATP Indian Wells | 2021/10/13 21:55 | Taylor Fritz v Jannik Sinner | 6-4,6-3 |
| ATP Indian Wells | 2021/10/10 18:00 | John Millman v Jannik Sinner | 2-6,2-6 |
| ATP Sofia | 2021/10/03 13:30 | Jannik Sinner v Gael Monfils | 6-3,6-4 |
| ATP Sofia | 2021/10/02 15:00 | Jannik Sinner v Filip Krajinovic | 6-3,7-5 |
| ATP Sofia | 2021/10/01 15:00 | Jannik Sinner v James Duckworth | 7-6,6-4 |
| ATP Sofia | 2021/09/30 15:00 | Jannik Sinner v Egor Gerasimov | 6-2,7-6 |
| US Open | 2021/09/06 16:00 | Alexander Zverev v Jannik Sinner | 6-4,6-4,7-6 |
| US Open | 2021/09/04 18:00 | Gael Monfils v Jannik Sinner | 6-7,2-6,6-4,6-4,4-6 |
Away History
| ATP Antwerp | 2021/10/19 14:15 | Lorenzo Musetti v Gianluca Mager | 7-6,7-6 |
| ATP Indian Wells | 2021/10/08 20:55 | Albert Ramos-Vinolas v Lorenzo Musetti | 6-1,6-3 |
| ATP Sofia | 2021/09/28 15:10 | Dimitar Kuzmanov v Lorenzo Musetti | 6-7,7-6,6-3 |
| ATP Nur-Sultan | 2021/09/22 07:45 | Laslo Djere v Lorenzo Musetti | 6-4,6-7,6-4 |
| ATP Nur-Sultan | 2021/09/21 07:55 | Marc Polmans v Lorenzo Musetti | 4-6,6-2,4-6 |
| US Open | 2021/09/02 16:00 | Lorenzo Musetti v Reilly Opelka | 6-7,5-7,4-6 |
| US Open | 2021/08/31 15:00 | Lorenzo Musetti v Emilio Nava | 6-7,6-4,6-1,6-3 |
| ATP Winston-Salem | 2021/08/23 19:00 | Federico Coria v Lorenzo Musetti | 6-4,4-6,6-4 |