[1] TB Lightning 3-9 FLA Panthers [2] 2021-12-31 00:00
Stadium: Amerant Bank Arena
Home Manager: Andrew Brunette Away Manager: Jon Cooper
Head to Head
| NHL | 2021/11/14 00:00 | FLA Panthers v TB Lightning | W | 2-3 |
| NHL | 2021/10/19 23:00 | FLA Panthers v TB Lightning | L | 4-1 |
| NHL Pre-Season | 2021/10/09 22:00 | TB Lightning v FLA Panthers | W | 4-2 |
| NHL Pre-Season | 2021/10/07 23:00 | FLA Panthers v TB Lightning | W | 2-6 |
| NHL Pre-Season | 2021/10/05 23:00 | FLA Panthers v TB Lightning | L | 3-2 |
| NHL | 2021/05/27 00:00 | FLA Panthers v TB Lightning | W | 0-4 |
| NHL | 2021/05/25 00:00 | TB Lightning v FLA Panthers | L | 1-4 |
| NHL | 2021/05/22 16:30 | FLA Panthers v TB Lightning | W | 2-6 |
Home History
| NHL | 2021/12/29 00:00 | MON Canadiens v TB Lightning | W | 4-5 |
| NHL | 2021/12/22 03:00 | TB Lightning v VGS Golden Knights | W | 4-3 |
| NHL | 2021/12/17 00:00 | OTT Senators v TB Lightning | W | 1-2 |
| NHL | 2021/12/15 00:00 | LA Kings v TB Lightning | W | 2-3 |
| NHL | 2021/12/11 18:00 | TB Lightning v OTT Senators | L | 0-4 |
| NHL | 2021/12/10 00:00 | TB Lightning v TOR Maple Leafs | W | 5-3 |
| NHL | 2021/12/08 00:00 | TB Lightning v MON Canadiens | W | 3-2 |
| NHL | 2021/12/05 23:00 | TB Lightning v PHI Flyers | W | 7-1 |
Away History
| NHL | 2021/12/30 00:00 | NY Rangers v FLA Panthers | W | 3-4 |
| NHL | 2021/12/17 00:00 | LA Kings v FLA Panthers | L | 4-1 |
| NHL | 2021/12/15 00:00 | OTT Senators v FLA Panthers | L | 8-2 |
| NHL | 2021/12/13 01:00 | FLA Panthers v COL Avalanche | L | 2-3 |
| NHL | 2021/12/11 02:00 | FLA Panthers v ARZ Coyotes | W | 3-1 |
| NHL | 2021/12/08 01:00 | FLA Panthers v STL Blues | L | 3-4 |
| NHL | 2021/12/04 18:00 | STL Blues v FLA Panthers | W | 3-4 |
| NHL | 2021/12/03 00:00 | BUF Sabres v FLA Panthers | W | 4-7 |