[11] Harlequins 20-9 Northampton [7] 2016-10-08 14:00
Stadium: London Round: 6
Referee: Ian Tempest Home Manager: John Kingston Away Manager: Dusty Hare
Head to Head
| Premiership Rugby | 2016/03/27 14:15 | Northampton v Harlequins | L | 29-23 |
| Premiership Rugby | 2016/02/06 14:00 | Harlequins v Northampton | L | 23-27 |
| Premiership Rugby | 2015/02/27 19:45 | Northampton v Harlequins | L | 17-13 |
| Premiership Rugby | 2014/12/27 16:30 | Harlequins v Northampton | L | 25-30 |
| European Rugby Challenge Cup | 2014/04/25 19:00 | Northampton v Harlequins | L | 18-10 |
Home History
| Premiership Rugby Shield | 2016/10/03 18:30 | Harlequins v Exeter Braves | L | 22-39 |
| Premiership Rugby | 2016/10/02 13:30 | Wasps v Harlequins | L | 47-18 |
| Premiership Rugby | 2016/09/24 14:00 | Harlequins v Saracens | W | 17-10 |
| Premiership Rugby Shield | 2016/09/19 18:30 | Harlequins v Gloucester United | W | 22-8 |
| Premiership Rugby | 2016/09/17 14:00 | Exeter Chiefs v Harlequins | L | 36-25 |
| Premiership Rugby Shield | 2016/09/12 18:15 | Bristol United v Harlequins | L | 37-26 |
| Premiership Rugby | 2016/09/09 19:15 | Sale Sharks v Harlequins | L | 19-10 |
| Premiership Rugby | 2016/09/03 15:30 | Harlequins v Bristol | W | 21-19 |
Away History
| Premiership Rugby | 2016/09/30 18:45 | Northampton v Exeter Chiefs | W | 20-19 |
| Premiership Rugby | 2016/09/24 14:00 | Northampton v Wasps | L | 15-20 |
| Premiership Rugby | 2016/09/17 14:00 | Saracens v Northampton | L | 27-12 |
| Premiership Rugby | 2016/09/11 14:00 | Bristol v Northampton | W | 10-32 |
| Premiership Rugby | 2016/09/03 14:30 | Northampton v Bath | L | 14-18 |
| Premiership Rugby | 2016/05/07 14:30 | Gloucester v Northampton | W | 20-28 |
| Premiership Rugby | 2016/04/30 14:15 | Northampton v Bath | W | 15-14 |
| Premiership Rugby | 2016/04/16 16:30 | Northampton v Leicester | L | 24-30 |