[27] Reilly Opelka 4-6,2-6 Jannik Sinner [11] 2021-10-27 12:00
Stadium: Center Court Round: 25 Ground: Hardcourt indoor
Home History
| ATP Antwerp | 2021/10/19 14:15 | Reilly Opelka v Jenson Brooksby | 4-6,4-6 |
| ATP Indian Wells | 2021/10/11 20:35 | Grigor Dimitrov v Reilly Opelka | 6-3,6-4 |
| ATP Indian Wells | 2021/10/09 18:00 | Taro Daniel v Reilly Opelka | 5-7,3-6 |
| Laver Cup | 2021/09/24 17:00 | Casper Ruud v Reilly Opelka | 6-3,7-6 |
| US Open | 2021/09/06 17:25 | Reilly Opelka v Lloyd Harris | 7-6,4-6,1-6,3-6 |
| US Open | 2021/09/04 23:10 | Nikoloz Basilashvili v Reilly Opelka | 6-7,3-6,4-6 |
| US Open | 2021/09/02 16:00 | Lorenzo Musetti v Reilly Opelka | 6-7,5-7,4-6 |
| US Open | 2021/08/31 15:00 | Soonwoo Kwon v Reilly Opelka | 6-7,4-6,4-6 |
Away History
| ATP Antwerp | 2021/10/24 14:30 | Jannik Sinner v Diego Schwartzman | 6-2,6-2 |
| ATP Antwerp | 2021/10/23 13:00 | Jannik Sinner v Lloyd Harris | 6-2,6-2 |
| ATP Antwerp | 2021/10/22 14:40 | Jannik Sinner v Arthur Rinderknech | 6-4,6-2 |
| ATP Antwerp | 2021/10/20 16:20 | Jannik Sinner v Lorenzo Musetti | 7-5,6-2 |
| ATP Indian Wells | 2021/10/13 21:55 | Taylor Fritz v Jannik Sinner | 6-4,6-3 |
| ATP Indian Wells | 2021/10/10 18:00 | John Millman v Jannik Sinner | 2-6,2-6 |
| ATP Sofia | 2021/10/03 13:30 | Jannik Sinner v Gael Monfils | 6-3,6-4 |
| ATP Sofia | 2021/10/02 15:00 | Jannik Sinner v Filip Krajinovic | 6-3,7-5 |