Home History
| Ghana Premier League | 2022/01/30 15:00 | Berekum Chelsea v Accra Lions FC | L | 3-1 |
| Ghana Premier League | 2022/01/22 15:00 | Accra Lions FC v Ashanti Gold | L | 0-1 |
| Ghana Premier League | 2022/01/16 15:00 | Aduana Stars v Accra Lions FC | D | 1-1 |
| Ghana Premier League | 2022/01/08 15:00 | Accra Lions FC v WAFA | D | 0-0 |
| Ghana Premier League | 2022/01/03 15:00 | Legon Cities FC v Accra Lions FC | W | 0-1 |
| Ghana Premier League | 2021/12/27 15:00 | Accra Lions FC v Real Tamale United | W | 2-1 |
| Ghana Premier League | 2021/12/19 18:00 | Hearts of Oak v Accra Lions FC | L | 2-0 |
| Ghana Premier League | 2021/12/15 15:00 | Accra Lions FC v King Faisal | D | 0-0 |
Away History
| Ghana Premier League | 2022/01/30 15:00 | Medeama SC v Elmina Sharks | W | 1-0 |
| Ghana Premier League | 2022/01/23 15:00 | Asante Kotoko v Medeama SC | L | 1-0 |
| Ghana Premier League | 2022/01/16 15:00 | Medeama SC v Great Olympics | D | 0-0 |
| Ghana Premier League | 2022/01/12 15:00 | Medeama SC v Hearts of Oak | W | 1-0 |
| Ghana Premier League | 2022/01/07 15:00 | Medeama SC v Berekum Chelsea | D | 1-1 |
| Ghana Premier League | 2022/01/03 15:00 | Ashanti Gold v Medeama SC | W | 0-1 |
| Ghana FA Cup | 2021/12/29 15:00 | Karela United FC v Medeama SC | D | 2-2 |
| Ghana Premier League | 2021/12/26 15:00 | Medeama SC v Aduana Stars | W | 1-0 |