Home History
| Ghana Premier League | 2021/10/31 15:00 | Bechem FC v Medeama SC | L | 4-0 |
| Ghana FA Cup | 2021/08/01 18:00 | Hearts of Oak v Medeama SC | L | 3-0 |
| Ghana FA Cup | 2021/07/25 15:00 | Medeama SC v Attram De Visser | W | 3-2 |
| Ghana Premier League | 2021/07/18 15:00 | Medeama SC v Berekum Chelsea | W | 1-0 |
| Ghana Premier League | 2021/07/11 15:00 | Eleven Wonders v Medeama SC | L | 3-1 |
| Ghana FA Cup | 2021/07/07 15:00 | Medeama SC v Great Olympics | W | 5-3 |
| Ghana Premier League | 2021/07/04 15:00 | Medeama SC v Elmina Sharks | W | 3-2 |
| Ghana Premier League | 2021/06/27 15:00 | Bechem FC v Medeama SC | D | 0-0 |
Away History
| Ghana Premier League | 2021/10/31 15:00 | Bibiani Gold Stars v Berekum Chelsea | W | 1-0 |