[29] Iowa 17-12 Northwestern [99] 2021-11-06 23:00
Stadium: Ryan Field Round: 1
Home Manager: Pat Fitzgerald Away Manager: Kirk Ferentz
Head to Head
| NCAAF | 2020/10/31 19:30 | Northwestern v Iowa | L | 21-20 |
| NCAAF | 2019/10/26 16:00 | Iowa v Northwestern | W | 20-0 |
| NCAAF | 2018/11/10 20:30 | Northwestern v Iowa | L | 14-10 |
| NCAAF | 2017/10/21 16:00 | Iowa v Northwestern | L | 10-17 |
| NCAAF | 2016/10/01 16:00 | Northwestern v Iowa | L | 38-31 |
| NCAAF | 2015/10/17 16:00 | Northwestern v Iowa | W | 10-40 |
| NCAAF | 2014/11/01 16:00 | Iowa v Northwestern | W | 48-7 |
| NCAAF | 2012/10/27 12:00 | Northwestern v Iowa | L | 28-17 |
Home History
| NCAAF | 2021/10/30 16:00 | Iowa v Wisconsin | L | 7-27 |
| NCAAF | 2021/10/16 19:30 | Purdue v Iowa | L | 24-7 |
| NCAAF | 2021/10/09 20:00 | Penn State v Iowa | W | 20-23 |
| NCAAF | 2021/10/02 00:00 | Iowa v Maryland | W | 51-14 |
| NCAAF | 2021/09/25 19:30 | Colorado State v Iowa | W | 14-24 |
| NCAAF | 2021/09/18 19:30 | Kent State v Iowa | W | 7-30 |
| NCAAF | 2021/09/11 20:30 | Iowa v Iowa State | W | 27-17 |
| NCAAF | 2021/09/04 19:30 | Indiana v Iowa | W | 6-34 |
Away History
| NCAAF | 2021/10/30 19:30 | Minnesota v Northwestern | L | 41-14 |
| NCAAF | 2021/10/23 16:00 | Northwestern v Michigan | L | 7-33 |
| NCAAF | 2021/10/16 16:00 | Rutgers v Northwestern | W | 7-21 |
| NCAAF | 2021/10/02 23:30 | Northwestern v Nebraska | L | 7-56 |
| NCAAF | 2021/09/25 16:00 | Ohio v Northwestern | W | 6-35 |
| NCAAF | 2021/09/18 20:00 | Northwestern v Duke | L | 23-30 |
| NCAAF | 2021/09/11 16:00 | Indiana State v Northwestern | W | 6-24 |
| NCAAF | 2021/09/04 01:00 | Michigan State v Northwestern | L | 38-21 |