| El Salvador Reserves League | 2021/08/25 18:00 | CD Platense Zacatecoluca Reserves v AD Isidro Metapan Reserves | L | 2-0 |
| El Salvador Reserves League | 2021/10/31 20:30 | Municipal Limeno Reserves v AD Isidro Metapan Reserves | D | 1-1 |
| El Salvador Reserves League | 2021/10/20 21:30 | CD Aguila Reserves v AD Isidro Metapan Reserves | L | 2-1 |
| El Salvador Reserves League | 2021/10/15 21:00 | AD Isidro Metapan Reserves v Santa Tecla Reserves | D | 0-0 |
| El Salvador Reserves League | 2021/10/01 19:45 | Atletico Marte Reserves v AD Isidro Metapan Reserves | D | 3-3 |
| El Salvador Reserves League | 2021/09/26 21:00 | AD Isidro Metapan Reserves v AD Chalatenago Reserves | W | 2-0 |
| El Salvador Reserves League | 2021/09/18 16:00 | CD FAS Reserves v AD Isidro Metapan Reserves | D | 2-2 |
| El Salvador Reserves League | 2021/09/16 21:00 | AD Isidro Metapan Reserves v Once Deportivo de Ahuachapán Reserves | D | 2-2 |
| El Salvador Reserves League | 2021/09/10 19:00 | CD Luis Angel Firpo Reserves v AD Isidro Metapan Reserves | W | 2-3 |
| El Salvador Reserves League | 2021/10/30 17:00 | CD Platense Zacatecoluca Reserves v CD FAS Reserves | D | 1-1 |
| El Salvador Reserves League | 2021/10/24 17:00 | Once Deportivo de Ahuachapán Reserves v CD Platense Zacatecoluca Reserves | W | 2-3 |
| El Salvador Reserves League | 2021/10/17 18:30 | Alianza FC San Salvador Reserves v CD Platense Zacatecoluca Reserves | L | 5-0 |
| El Salvador Reserves League | 2021/10/09 17:00 | CD Platense Zacatecoluca Reserves v CD Luis Angel Firpo Reserves | D | 3-3 |
| El Salvador Reserves League | 2021/10/03 20:30 | CD Platense Zacatecoluca Reserves v AD Chalatenago Reserves | D | 0-0 |
| El Salvador Reserves League | 2021/09/25 21:00 | Municipal Limeno Reserves v CD Platense Zacatecoluca Reserves | L | 1-0 |
| El Salvador Reserves League | 2021/09/19 17:00 | CD Platense Zacatecoluca Reserves v Jocoro FC Reserves | D | 0-0 |
| El Salvador Reserves League | 2021/09/15 21:30 | CD Aguila Reserves v CD Platense Zacatecoluca Reserves | L | 3-1 |