Stadium: Dwyer Arena Round: 1
| NCAAH | 2021/12/10 00:00 | Canisius v Niagara Purple Eagles | L | 4-0 |
| NCAAH | 2021/02/28 00:00 | Canisius v Niagara Purple Eagles | W | 0-4 |
| NCAAH | 2021/02/27 00:35 | Niagara Purple Eagles v Canisius | L | 1-5 |
| NCAAH | 2019/11/16 21:05 | Canisius v Niagara Purple Eagles | W | 3-5 |
| NCAAH | 2019/11/16 00:35 | Canisius v Niagara Purple Eagles | L | 4-2 |
| NCAAH | 2019/02/24 00:00 | Niagara Purple Eagles v Canisius | D | 3-3 |
| NCAAH | 2019/02/23 00:35 | Canisius v Niagara Purple Eagles | D | 2-2 |
| NCAAH | 2018/11/18 00:05 | Niagara Purple Eagles v Canisius | W | 9-6 |
| NCAAH | 2021/12/10 00:00 | Canisius v Niagara Purple Eagles | L | 4-0 |
| NCAAH | 2021/12/05 00:00 | Holy Cross v Niagara Purple Eagles | L | 3-2 |
| NCAAH | 2021/12/04 00:00 | Holy Cross v Niagara Purple Eagles | W | 1-3 |
| NCAAH | 2021/11/20 22:00 | Niagara Purple Eagles v Army | L | 1-4 |
| NCAAH | 2021/11/20 00:00 | Niagara Purple Eagles v Army | D | 3-3 |
| NCAAH | 2021/11/06 21:05 | Niagara Purple Eagles v Air Force | D | 3-3 |
| NCAAH | 2021/11/05 23:05 | Niagara Purple Eagles v Air Force | W | 4-3 |
| NCAAH | 2021/10/30 17:05 | Sacred Heart v Niagara Purple Eagles | L | 3-1 |
| NCAAH | 2021/12/10 00:00 | Canisius v Niagara Purple Eagles | W | 4-0 |
| NCAAH | 2021/12/05 00:05 | Air Force v Canisius | D | 3-3 |
| NCAAH | 2021/12/04 02:05 | Air Force v Canisius | L | 5-2 |
| NCAAH | 2021/11/27 18:00 | Canisius v American International | L | 2-3 |
| NCAAH | 2021/11/26 18:00 | Canisius v American International | W | 6-5 |
| NCAAH | 2021/11/21 00:00 | Canisius v Mercyhurst | L | 2-5 |
| NCAAH | 2021/11/20 00:05 | Mercyhurst v Canisius | W | 1-6 |
| NCAAH | 2021/11/13 21:00 | Canisius v Rochester Inst | W | 4-1 |