| Panama Liga Prom | 2021/04/28 20:00 | Union Cocle v Mario Mendez FC | W | 0-1 |
| Panama Liga Prom | 2021/10/29 20:00 | CD Universitario Reserves v Mario Mendez FC | W | 0-1 |
| Panama Liga Prom | 2021/10/20 23:00 | Mario Mendez FC v Atletico Chiriqui B | W | 2-0 |
| Panama Liga Prom | 2021/10/16 00:00 | Mario Mendez FC v CA Independiente de la Chorrera Reserves | L | 1-2 |
| Panama Liga Prom | 2021/10/10 00:00 | SD Atletico Nacional v Mario Mendez FC | D | 1-1 |
| Panama Liga Prom | 2021/10/03 00:00 | Mario Mendez FC v SD Panama Oeste | L | 1-2 |
| Panama Liga Prom | 2021/09/24 20:00 | Udelas FC v Mario Mendez FC | D | 1-1 |
| Panama Liga Prom | 2021/09/19 00:00 | San Francisco Reserves v Mario Mendez FC | W | 0-1 |
| Panama Liga Prom | 2021/09/10 23:00 | Mario Mendez FC v Aguilas de la U | W | 1-0 |
| Panama Liga Prom | 2021/10/31 20:00 | Union Cocle v Veraguas CD Reserves | L | 0-4 |
| Panama Liga Prom | 2021/10/20 23:01 | Herrera FC Reserves v Union Cocle | L | 3-0 |
| Panama Liga Prom | 2021/10/17 00:00 | San Francisco Reserves v Union Cocle | L | 3-0 |
| Panama Liga Prom | 2021/10/02 22:00 | CA Independiente de la Chorrera Reserves v Union Cocle | L | 4-0 |
| Panama Liga Prom | 2021/09/25 20:00 | Union Cocle v SD Panama Oeste | L | 0-2 |
| Panama Liga Prom | 2021/09/17 20:00 | Union Cocle v SD Atletico Nacional | L | 1-6 |
| Panama Liga Prom | 2021/09/09 20:00 | Udelas FC v Union Cocle | L | 2-0 |
| Panama Liga Prom | 2021/08/27 20:00 | CD Universitario Reserves v Union Cocle | W | 0-2 |