[5] Nacional Asuncion 1-5 Cerro Porteno [2] 2021-11-21 23:15
Stadium: Estadio Arsenio Erico Round: 16
Referee: Eber Aquino Home Manager: Hernan Rodrigo Lopez Mora Away Manager: Francisco Arce
Head to Head
| Paraguay Division Profesional | 2021/08/29 00:15 | Cerro Porteno v Nacional Asuncion | W | 0-2 |
| Paraguay Division Profesional | 2021/05/09 00:00 | Cerro Porteno v Nacional Asuncion | D | 2-2 |
| Paraguay Division Profesional | 2021/03/06 21:15 | Nacional Asuncion v Cerro Porteno | W | 2-0 |
| Paraguay Division Profesional | 2020/12/07 23:00 | Nacional Asuncion v Cerro Porteno | W | 4-3 |
| Paraguay Division Profesional | 2020/09/15 22:30 | Cerro Porteno v Nacional Asuncion | L | 1-0 |
| Paraguay Division Profesional | 2020/03/06 23:15 | Nacional Asuncion v Cerro Porteno | D | 0-0 |
| Paraguay Division Profesional | 2019/11/10 22:30 | Cerro Porteno v Nacional Asuncion | L | 5-0 |
| Paraguay Division Profesional | 2019/08/26 23:00 | Nacional Asuncion v Cerro Porteno | D | 1-1 |
Home History
| Paraguay Division Profesional | 2021/11/08 23:30 | Guairena FC v Nacional Asuncion | D | 0-0 |
| Paraguay Division Profesional | 2021/10/29 22:30 | Nacional Asuncion v River Plate Asuncion | D | 1-1 |
| Paraguay Division Profesional | 2021/10/24 23:15 | Libertad Asuncion v Nacional Asuncion | W | 1-2 |
| Paraguay Division Profesional | 2021/10/16 22:30 | Nacional Asuncion v Sportivo Luqueno | D | 0-0 |
| Paraguay Division Profesional | 2021/10/03 21:00 | Guarani Asuncion v Nacional Asuncion | D | 1-1 |
| Paraguay Division Profesional | 2021/09/25 22:00 | Nacional Asuncion v 12 de Octubre | D | 1-1 |
| Paraguay Division Profesional | 2021/09/21 00:00 | Olimpia Asuncion v Nacional Asuncion | W | 1-2 |
| Paraguay Division Profesional | 2021/09/10 23:30 | Nacional Asuncion v Sol de America | D | 1-1 |
Away History
| Paraguay Division Profesional | 2021/11/07 23:30 | Cerro Porteno v Sol de America | W | 3-0 |
| Paraguay Division Profesional | 2021/10/31 21:00 | Cerro Porteno v Olimpia Asuncion | W | 1-0 |
| Paraguay Division Profesional | 2021/10/25 21:30 | Guairena FC v Cerro Porteno | W | 0-2 |
| Paraguay Division Profesional | 2021/10/18 23:30 | Cerro Porteno v River Plate Asuncion | W | 2-0 |
| Paraguay Cup | 2021/10/06 23:00 | Cerro Porteno v Sol de America | L | 0-2 |
| Paraguay Division Profesional | 2021/10/03 23:15 | Libertad Asuncion v Cerro Porteno | W | 0-2 |
| Paraguay Division Profesional | 2021/09/26 00:15 | Cerro Porteno v Sportivo Luqueno | L | 0-1 |
| Paraguay Division Profesional | 2021/09/19 00:15 | Cerro Porteno v Guarani Asuncion | D | 0-0 |