Head to Head
| Premiership Rugby | 2022/02/06 13:00 | Harlequins v Sale Sharks | L | 14-36 |
| Premiership Rugby | 2021/10/15 18:45 | Sale Sharks v Harlequins | L | 28-22 |
| Premiership Rugby | 2021/06/04 18:45 | Sale Sharks v Harlequins | L | 45-12 |
| Premiership Rugby | 2021/02/20 13:00 | Harlequins v Sale Sharks | W | 24-12 |
| Premiership Rugby Cup | 2020/09/21 18:45 | Sale Sharks v Harlequins | L | 27-19 |
| Premiership Rugby | 2020/08/14 18:45 | Harlequins v Sale Sharks | W | 16-10 |
| Premiership Rugby | 2020/01/03 19:45 | Sale Sharks v Harlequins | L | 48-10 |
| Premiership Rugby | 2019/04/05 18:45 | Sale Sharks v Harlequins | L | 28-17 |
Home History
| Premiership Rugby Cup | 2022/03/18 19:45 | London Irish v Harlequins | L | 34-19 |
| Premiership Rugby | 2022/03/13 15:00 | Bristol v Harlequins | W | 29-38 |
| Premiership Rugby | 2022/03/04 19:45 | Harlequins v Newcastle Falcons | W | 24-10 |
| Premiership Rugby | 2022/02/25 19:45 | Worcester Warriors v Harlequins | W | 21-29 |
| Premiership Rugby | 2022/02/19 15:00 | Harlequins v Wasps | W | 29-24 |
| Premiership Rugby | 2022/02/13 13:00 | Saracens v Harlequins | L | 19-10 |
| Premiership Rugby | 2022/02/06 13:00 | Harlequins v Sale Sharks | L | 14-36 |
| Premiership Rugby | 2022/01/28 19:45 | Bath v Harlequins | L | 21-17 |
Away History
| Premiership Rugby | 2022/03/26 15:00 | Bath v Sale Sharks | D | 24-24 |
| Premiership Rugby Cup | 2022/03/19 13:00 | Sale Sharks v Wasps | L | 26-41 |
| Premiership Rugby | 2022/03/12 15:00 | Sale Sharks v Gloucester | W | 26-24 |
| Premiership Rugby | 2022/03/06 15:00 | Exeter Chiefs v Sale Sharks | L | 19-12 |
| Premiership Rugby | 2022/02/25 19:45 | Sale Sharks v London Irish | D | 27-27 |
| Premiership Rugby | 2022/02/19 15:00 | Northampton v Sale Sharks | W | 21-22 |
| Premiership Rugby | 2022/02/12 15:00 | Sale Sharks v Worcester Warriors | W | 36-12 |
| Premiership Rugby | 2022/02/06 13:00 | Harlequins v Sale Sharks | W | 14-36 |