Stadium: Jones Convocation Center
Home Manager: Tiffany Sardin Away Manager: Chad Killinger
| WNCAAB | 2021/11/27 17:00 | Chicago State Women v Delaware Women | L | 63-72 |
| WNCAAB | 2021/11/26 17:00 | Chicago State Women v Florida Intl Women | L | 46-64 |
| WNCAAB | 2021/11/23 00:30 | Chicago State Women v Wisconsin Women | W | 71-63 |
| WNCAAB | 2021/11/20 18:00 | Chicago State Women v Loyola Chicago Women | L | 59-71 |
| WNCAAB | 2021/11/18 00:00 | Chicago State Women v Western Illinois Women | L | 50-77 |
| WNCAAB | 2021/11/13 18:00 | UAB Women v Chicago State Women | L | 81-50 |
| WNCAAB | 2021/11/09 18:00 | Chicago State Women v Wichita State Women | L | 34-78 |
| WNCAAB | 2021/03/11 00:30 | Chicago State Women v Utah Valley Women | L | 43-61 |
| WNCAAB | 2021/11/27 20:30 | Indiana State Women v Georgia Southern Women | W | 71-67 |
| WNCAAB | 2021/11/26 20:30 | Indiana State Women v Jacksonville State Women | L | 57-67 |
| WNCAAB | 2021/11/24 18:00 | Indiana State Women v Western Kentucky Women | L | 65-83 |
| WNCAAB | 2021/11/17 23:00 | Eastern Illinois Women v Indiana State Women | L | 64-55 |
| WNCAAB | 2021/11/14 19:00 | Indiana State Women v St Louis Women | L | 58-65 |
| WNCAAB | 2021/11/09 23:00 | Indiana State Women v Stephens Women | W | 88-33 |
| WNCAAB | 2021/03/11 22:30 | Indiana State Women v Southern Illinois Women | L | 89-90 |
| WNCAAB | 2021/03/06 22:00 | Bradley Women v Indiana State Women | L | 80-58 |