Stadium: Sam M. Vadalabene Center
Home Manager: Samantha Quigley Smith Away Manager: Cayla Petree
| WNCAAB | 2022/01/22 19:00 | SIU Edwardsville Women v Morehead State Women | L | 77-52 |
| WNCAAB | 2021/01/19 23:00 | Morehead State Women v SIU Edwardsville Women | W | 53-47 |
| WNCAAB | 2021/01/16 18:30 | SIU Edwardsville Women v Morehead State Women | W | 53-63 |
| WNCAAB | 2020/02/06 23:30 | Morehead State Women v SIU Edwardsville Women | W | 63-55 |
| WNCAAB | 2020/01/09 22:00 | Morehead State Women v SIU Edwardsville Women | W | 75-69 |
| WNCAAB | 2019/01/31 17:00 | SIU Edwardsville Women v Morehead State Women | W | 67-73 |
| WNCAAB | 2018/01/06 19:00 | Morehead State Women v SIU Edwardsville Women | L | 51-66 |
| WNCAAB | 2022/02/24 23:00 | Morehead State Women v Eastern Illinois Women | L | 56-68 |
| WNCAAB | 2022/02/19 19:00 | SE Missouri State Women v Morehead State Women | L | 70-62 |
| WNCAAB | 2022/02/16 23:30 | Morehead State Women v Tennessee Martin Women | L | 36-54 |
| WNCAAB | 2022/02/12 19:00 | Murray State Women v Morehead State Women | L | 72-58 |
| WNCAAB | 2022/02/10 23:00 | Morehead State Women v Belmont Women | L | 50-76 |
| WNCAAB | 2022/02/05 19:00 | Austin Peay Women v Morehead State Women | L | 71-61 |
| WNCAAB | 2022/02/03 17:00 | Tennessee Tech Women v Morehead State Women | L | 87-69 |
| WNCAAB | 2022/01/31 23:00 | Morehead State Women v Tennessee State Women | L | 60-77 |
| WNCAAB | 2022/02/24 23:30 | Austin Peay Women v SIU Edwardsville Women | W | 61-71 |
| WNCAAB | 2022/02/19 20:00 | SIU Edwardsville Women v Belmont Women | L | 50-88 |
| WNCAAB | 2022/02/17 23:30 | SIU Edwardsville Women v Tennessee State Women | W | 86-76 |
| WNCAAB | 2022/02/12 18:00 | Tennessee Tech Women v SIU Edwardsville Women | L | 68-64 |
| WNCAAB | 2022/02/10 17:00 | Tennessee Martin Women v SIU Edwardsville Women | L | 67-62 |
| WNCAAB | 2022/02/07 23:30 | Eastern Illinois Women v SIU Edwardsville Women | L | 70-68 |
| WNCAAB | 2022/02/05 23:00 | SIU Edwardsville Women v Murray State Women | L | 73-87 |
| WNCAAB | 2022/02/01 00:00 | SIU Edwardsville Women v Eastern Illinois Women | L | 65-89 |