Stadium: TD Arena
Home Manager: Robin Harmony Away Manager: Misty Wilson
| WNCAAB | 2021/11/20 19:00 | Tarleton State Women v Howard Payne Women | W | 87-44 |
| WNCAAB | 2021/11/17 00:00 | Tarleton State Women v Paul Quinn Women | W | 70-46 |
| WNCAAB | 2021/11/13 20:00 | Tarleton State Women v Champion Christian Women | W | 82-66 |
| WNCAAB | 2021/11/11 01:00 | Tarleton State Women v Arkansas Women | L | 33-85 |
| WNCAAB | 2021/03/07 01:00 | Tarleton State Women v UT Rio Grande Valley Women | W | 63-52 |
| WNCAAB | 2021/03/06 01:00 | Tarleton State Women v UT Rio Grande Valley Women | L | 56-62 |
| WNCAAB | 2021/03/04 00:00 | Utah Valley Women v Tarleton State Women | L | 67-54 |
| WNCAAB | 2021/03/03 00:00 | Tarleton State Women v Utah Valley Women | L | 58-60 |
| WNCAAB | 2021/11/19 23:00 | Charleston Women v Norfolk State Women | W | 66-62 |
| WNCAAB | 2021/11/12 16:00 | Charleston Women v Pfeiffer Women | W | 113-52 |
| WNCAAB | 2021/11/10 00:30 | Charleston Women v Wofford Women | W | 80-48 |
| WNCAAB | 2021/03/10 19:30 | UNC Wilmington Women v Charleston Women | L | 60-47 |
| WNCAAB | 2021/02/28 18:00 | Charleston Women v UNC Wilmington Women | L | 54-61 |
| WNCAAB | 2021/02/27 00:00 | Charleston Women v UNC Wilmington Women | L | 66-68 |
| WNCAAB | 2021/02/07 18:00 | Towson Women v Charleston Women | L | 84-63 |
| WNCAAB | 2021/02/06 18:00 | Towson Women v Charleston Women | L | 90-81 |