Stadium: Truist Arena
Home Manager: Camryn Whitaker Away Manager: Maria Marchesano
| WNCAAB | 2020/12/20 17:00 | Purdue Fort Wayne Women v Northern Kentucky Women | L | 63-80 |
| WNCAAB | 2020/12/19 19:00 | Purdue Fort Wayne Women v Northern Kentucky Women | L | 48-83 |
| WNCAAB | 2021/12/02 23:30 | Ball State Women v Purdue Fort Wayne Women | L | 86-58 |
| WNCAAB | 2021/11/28 20:00 | Purdue Fort Wayne Women v SIU Edwardsville Women | L | 56-68 |
| WNCAAB | 2021/11/24 19:00 | Evansville Women v Purdue Fort Wayne Women | L | 84-71 |
| WNCAAB | 2021/11/19 00:00 | UIC Women v Purdue Fort Wayne Women | W | 63-69 |
| WNCAAB | 2021/11/09 22:00 | Purdue Fort Wayne Women v Manchester Spartans Women | W | 102-35 |
| WNCAAB | 2021/02/25 22:00 | Purdue Fort Wayne Women v Youngstown State Women | L | 59-62 |
| WNCAAB | 2021/02/20 17:00 | Robert Morris Women v Purdue Fort Wayne Women | L | 77-63 |
| WNCAAB | 2021/02/19 19:00 | Robert Morris Women v Purdue Fort Wayne Women | W | 67-71 |
| WNCAAB | 2021/12/04 00:00 | Cleveland State Women v Northern Kentucky Women | L | 63-52 |
| WNCAAB | 2021/11/27 19:00 | Northern Kentucky Women v Central Arkansas Women | W | 63-59 |
| WNCAAB | 2021/11/24 23:00 | Northern Kentucky Women v Miami Ohio Women | W | 70-59 |
| WNCAAB | 2021/11/20 16:30 | Northern Kentucky Women v Wisc Milwaukee Women | L | 49-61 |
| WNCAAB | 2021/11/19 01:00 | Northern Kentucky Women v Wisc Green Bay Women | W | 61-52 |
| WNCAAB | 2021/11/14 19:00 | Eastern Kentucky Women v Northern Kentucky Women | W | 61-76 |
| WNCAAB | 2021/11/11 00:00 | Kent State Women v Northern Kentucky Women | L | 80-73 |
| WNCAAB | 2021/03/02 19:00 | Northern Kentucky Women v Wright State Women | L | 56-74 |