Stadium: Chaifetz Arena
Home Manager: Lisa Stone Away Manager: Camryn Whitaker
| WNCAAB | 2021/12/08 16:00 | Northern Kentucky Women v Kentucky State Women | W | 72-51 |
| WNCAAB | 2021/12/05 19:00 | Purdue Fort Wayne Women v Northern Kentucky Women | W | 60-69 |
| WNCAAB | 2021/12/04 00:00 | Cleveland State Women v Northern Kentucky Women | L | 63-52 |
| WNCAAB | 2021/11/27 19:00 | Northern Kentucky Women v Central Arkansas Women | W | 63-59 |
| WNCAAB | 2021/11/24 23:00 | Northern Kentucky Women v Miami Ohio Women | W | 70-59 |
| WNCAAB | 2021/11/20 16:30 | Northern Kentucky Women v Wisc Milwaukee Women | L | 49-61 |
| WNCAAB | 2021/11/19 01:00 | Northern Kentucky Women v Wisc Green Bay Women | W | 61-52 |
| WNCAAB | 2021/11/14 19:00 | Eastern Kentucky Women v Northern Kentucky Women | W | 61-76 |
| WNCAAB | 2021/12/10 01:00 | St Louis Women v SIU Edwardsville Women | L | 57-63 |
| WNCAAB | 2021/12/05 20:00 | St Louis Women v Tennessee Martin Women | W | 59-54 |
| WNCAAB | 2021/12/04 00:30 | SE Missouri State Women v St Louis Women | W | 54-83 |
| WNCAAB | 2021/11/27 21:45 | Florida Gulf Coast Women v St Louis Women | L | 73-65 |
| WNCAAB | 2021/11/27 00:00 | Florida Women v St Louis Women | L | 69-54 |
| WNCAAB | 2021/11/21 20:00 | St Louis Women v Kansas Women | L | 50-79 |
| WNCAAB | 2021/11/18 01:00 | Missouri Women v St Louis Women | L | 69-53 |
| WNCAAB | 2021/11/14 19:00 | Indiana State Women v St Louis Women | W | 58-65 |