Stadium: The Buc Dome
Home Manager: Clarisse Garcia Away Manager: Becky Burke
| WNCAAB | 2021/03/06 19:00 | USC Upstate Women v Charleston Southern Women | W | 72-64 |
| WNCAAB | 2020/02/12 00:00 | Charleston Southern Women v USC Upstate Women | W | 64-71 |
| WNCAAB | 2019/12/28 19:00 | USC Upstate Women v Charleston Southern Women | W | 70-53 |
| WNCAAB | 2019/03/12 23:00 | Charleston Southern Women v USC Upstate Women | L | 67-52 |
| WNCAAB | 2019/02/09 20:00 | Charleston Southern Women v USC Upstate Women | L | 74-62 |
| WNCAAB | 2019/01/19 19:00 | USC Upstate Women v Charleston Southern Women | L | 75-78 |
| WNCAAB | 2022/01/19 20:00 | USC Upstate Women v Longwood Women | W | 76-69 |
| WNCAAB | 2022/01/15 21:00 | North Carolina A&T Women v USC Upstate Women | W | 64-67 |
| WNCAAB | 2022/01/12 22:00 | High Point Women v USC Upstate Women | L | 83-73 |
| WNCAAB | 2022/01/01 21:00 | UNC Asheville Women v USC Upstate Women | W | 53-66 |
| WNCAAB | 2021/12/19 19:00 | USC Upstate Women v Kentucky Women | L | 44-67 |
| WNCAAB | 2021/12/18 19:00 | Morehead State Women v USC Upstate Women | W | 52-66 |
| WNCAAB | 2021/12/16 23:00 | USC Upstate Women v Bob Jones Bruins Women | W | 86-36 |
| WNCAAB | 2021/12/13 23:00 | Jacksonville Women v USC Upstate Women | W | 53-70 |
| WNCAAB | 2022/01/19 23:00 | Charleston Southern Women v North Carolina A&T Women | L | 50-88 |
| WNCAAB | 2022/01/16 19:00 | UNC Asheville Women v Charleston Southern Women | L | 59-47 |
| WNCAAB | 2022/01/12 23:00 | Charleston Southern Women v Presbyterian Women | L | 58-68 |
| WNCAAB | 2022/01/08 19:00 | Campbell Women v Charleston Southern Women | L | 61-40 |
| WNCAAB | 2022/01/06 00:00 | Charleston Southern Women v Gardner Webb Women | L | 62-99 |
| WNCAAB | 2021/12/29 22:00 | Charleston Southern Women v Winthrop Women | W | 67-54 |
| WNCAAB | 2021/12/21 17:00 | Duke Women v Charleston Southern Women | L | 78-35 |
| WNCAAB | 2021/12/19 19:00 | Charleston Southern Women v Georgia State Women | L | 50-55 |