Stadium: Northwest Florida State College Arena
Home Manager: Glenn Braica Away Manager: John Aiken
| NCAAB | 2021/11/23 00:30 | McNeese State v Carver | W | 98-54 |
| NCAAB | 2021/11/19 01:00 | McNeese State v LSU | L | 46-85 |
| NCAAB | 2021/11/16 00:30 | McNeese State v Champion Christian | W | 116-66 |
| NCAAB | 2021/11/12 01:00 | McNeese State v TCU | L | 61-77 |
| NCAAB | 2021/11/10 01:00 | McNeese State v SMU | L | 62-86 |
| NCAAB | 2021/03/09 23:00 | McNeese State v SE Louisiana | L | 68-71 |
| NCAAB | 2021/03/06 22:00 | Lamar v McNeese State | L | 60-51 |
| NCAAB | 2021/03/05 00:30 | Nicholls State v McNeese State | L | 80-67 |
| NCAAB | 2021/11/24 00:00 | St. Francis Brooklyn v St Johns | L | 70-76 |
| NCAAB | 2021/11/19 00:00 | St. Francis Brooklyn v Penn State | L | 59-74 |
| NCAAB | 2021/11/13 19:00 | St. Thomas (MN) v St. Francis Brooklyn | L | 91-73 |
| NCAAB | 2021/11/10 01:00 | St. Francis Brooklyn v Wisconsin | L | 58-81 |
| NCAAB | 2021/02/26 21:00 | St. Francis Brooklyn v Merrimack | L | 67-75 |
| NCAAB | 2021/02/25 23:00 | St. Francis Brooklyn v Merrimack | W | 84-71 |
| NCAAB | 2021/02/21 19:00 | Sacred Heart v St. Francis Brooklyn | L | 88-82 |
| NCAAB | 2021/02/20 21:00 | Sacred Heart v St. Francis Brooklyn | W | 76-88 |