Stadium: TD Arena
Home Manager: Pat Kelsey Away Manager: Quinton Ferrell
| NCAAB | 2021/12/07 00:00 | Presbyterian v Morehead State | L | 66-71 |
| NCAAB | 2021/12/04 00:00 | Bob Jones University v Presbyterian | W | 61-90 |
| NCAAB | 2021/12/01 00:00 | Presbyterian v Tennessee | L | 44-86 |
| NCAAB | 2021/11/26 21:00 | Presbyterian v Central Arkansas | W | 75-66 |
| NCAAB | 2021/11/25 19:00 | Presbyterian v New Orleans | W | 68-66 |
| NCAAB | 2021/11/24 21:00 | VMI v Presbyterian | W | 54-59 |
| NCAAB | 2021/11/19 00:00 | Presbyterian v Cincinnati | L | 45-79 |
| NCAAB | 2021/11/16 00:00 | The Citadel v Presbyterian | W | 70-74 |
| NCAAB | 2021/12/08 01:00 | Coll Of Charleston v Tulane | W | 86-72 |
| NCAAB | 2021/12/04 00:00 | Coll Of Charleston v Furman | L | 88-91 |
| NCAAB | 2021/12/01 00:30 | Tulane v Coll Of Charleston | W | 77-81 |
| NCAAB | 2021/11/27 21:00 | Coll Of Charleston v Chattanooga | W | 68-66 |
| NCAAB | 2021/11/23 01:00 | Coll Of Charleston v Oklahoma State | L | 66-96 |
| NCAAB | 2021/11/17 01:30 | North Carolina v Coll Of Charleston | L | 94-83 |
| NCAAB | 2021/11/13 22:00 | Loyola Maryland v Coll Of Charleston | W | 72-79 |
| NCAAB | 2021/11/13 00:30 | Lipscomb v Coll Of Charleston | W | 77-86 |