Stadium: William D. Mullins Center
Home Manager: Matt McCall Away Manager: Ashley Howard
| NCAAB | 2022/01/27 00:00 | Massachusetts v La Salle | L | 77-71 |
| NCAAB | 2021/01/09 21:00 | La Salle v Massachusetts | L | 67-83 |
| NCAAB | 2020/12/16 17:00 | Massachusetts v La Salle | L | 85-66 |
| NCAAB | 2020/03/05 00:00 | Massachusetts v La Salle | L | 75-64 |
| NCAAB | 2020/01/09 00:00 | La Salle v Massachusetts | L | 69-77 |
| NCAAB | 2019/01/31 00:00 | Massachusetts v La Salle | W | 51-60 |
| NCAAB | 2019/01/05 18:00 | La Salle v Massachusetts | W | 69-60 |
| NCAAB | 2018/03/07 23:00 | Massachusetts v La Salle | L | 69-67 |
| NCAAB | 2022/02/17 01:00 | La Salle v St Louis | L | 64-90 |
| NCAAB | 2022/02/12 23:00 | La Salle v Richmond | L | 63-77 |
| NCAAB | 2022/02/09 00:00 | St Louis v La Salle | L | 75-57 |
| NCAAB | 2022/02/05 19:00 | George Mason v La Salle | W | 78-83 |
| NCAAB | 2022/02/03 00:00 | La Salle v George Washington | L | 87-89 |
| NCAAB | 2022/01/29 17:00 | La Salle v Davidson | L | 69-77 |
| NCAAB | 2022/01/27 00:00 | Massachusetts v La Salle | L | 77-71 |
| NCAAB | 2022/01/22 21:30 | Richmond v La Salle | L | 64-56 |
| NCAAB | 2022/02/17 00:00 | Massachusetts v St. Bonaventure | L | 71-83 |
| NCAAB | 2022/02/12 17:00 | St Josephs v Massachusetts | W | 67-69 |
| NCAAB | 2022/02/10 00:00 | George Washington v Massachusetts | L | 77-68 |
| NCAAB | 2022/02/05 19:00 | Massachusetts v Rhode Island | W | 78-67 |
| NCAAB | 2022/01/30 19:00 | George Mason v Massachusetts | L | 72-62 |
| NCAAB | 2022/01/27 00:00 | Massachusetts v La Salle | W | 77-71 |
| NCAAB | 2022/01/23 19:30 | Massachusetts v St Louis | L | 59-90 |
| NCAAB | 2022/01/21 00:00 | St Louis v Massachusetts | W | 85-91 |