Southern 60-72 Louisville 2021-11-10 03:00
Stadium: KFC Yum! Center
Home Manager: Chris Mack Away Manager: Sean Woods
Home History
| NCAAB | 2021/03/12 02:30 | Southern v Grambling State | L | 67-72 |
| NCAAB | 2021/03/06 21:00 | Southern v Texas Southern | L | 74-80 |
| NCAAB | 2021/03/05 01:30 | Southern v Prairie View | L | 61-68 |
| NCAAB | 2021/02/27 22:30 | Alcorn State v Southern | W | 75-89 |
| NCAAB | 2021/02/24 20:30 | Alabama A&M v Southern | W | 57-73 |
| NCAAB | 2021/02/23 01:30 | Alabama State v Southern | W | 66-75 |
| NCAAB | 2021/02/13 19:45 | Southern v Arkansas-Pine Bluff | W | 73-71 |
| NCAAB | 2021/02/09 02:00 | Jackson State v Southern | L | 57-53 |
Away History
| NCAAB | 2021/03/10 23:30 | Duke v Louisville | L | 70-56 |
| NCAAB | 2021/03/06 21:00 | Virginia v Louisville | L | 68-58 |
| NCAAB | 2021/02/27 23:00 | Louisville v Duke | W | 80-73 |
| NCAAB | 2021/02/24 00:00 | Notre Dame v Louisville | W | 57-69 |
| NCAAB | 2021/02/20 23:00 | Louisville v North Carolina | L | 54-99 |
| NCAAB | 2021/02/01 19:00 | Georgia Tech v Louisville | W | 58-74 |
| NCAAB | 2021/01/28 02:00 | Louisville v Clemson | L | 50-54 |
| NCAAB | 2021/01/23 21:00 | Duke v Louisville | W | 65-70 |