Stadium: Ellis T. Johnson Arena
Home Manager: Preston Spradlin Away Manager: Brianna Burgos
| NCAAB | 2021/11/26 17:00 | Georgia Southern v Georgia Tech | L | 59-61 |
| NCAAB | 2021/11/21 22:00 | Georgia Southern v Wofford | L | 52-70 |
| NCAAB | 2021/11/20 23:00 | Georgia Southern v Hampton | W | 86-66 |
| NCAAB | 2021/11/17 00:00 | Georgia Southern v Bob Jones University | W | 103-51 |
| NCAAB | 2021/11/13 17:00 | Georgia Southern v South Florida | W | 53-41 |
| NCAAB | 2021/11/10 00:00 | Ball State v Georgia Southern | W | 71-82 |
| NCAAB | 2021/03/05 23:00 | Georgia Southern v Arkansas State | L | 58-62 |
| NCAAB | 2021/02/27 20:00 | Appalachian State v Georgia Southern | W | 57-65 |
| NCAAB | 2021/11/28 00:00 | Morehead State v Kansas City | W | 70-62 |
| NCAAB | 2021/11/27 01:00 | Morehead State v Arkansas State | W | 75-51 |
| NCAAB | 2021/11/21 20:00 | Morehead State v Mississippi State | L | 46-66 |
| NCAAB | 2021/11/19 00:30 | Morehead State v Transylvania | W | 84-59 |
| NCAAB | 2021/11/16 00:00 | Morehead State v Kentucky Christian | W | 82-57 |
| NCAAB | 2021/11/13 00:00 | Morehead State v UAB | L | 71-85 |
| NCAAB | 2021/11/10 01:00 | Morehead State v Auburn | L | 54-77 |
| NCAAB | 2021/03/20 02:32 | Morehead State v West Virginia | L | 67-84 |