Stadium: Sanford Sports Pentagon
Home Manager: Eric Henderson Away Manager: Kim English
| NCAAB | 2021/11/24 00:00 | George Mason v Nevada | L | 69-88 |
| NCAAB | 2021/11/23 02:30 | George Mason v Washington | L | 74-77 |
| NCAAB | 2021/11/20 00:00 | George Mason v James Madison | L | 64-67 |
| NCAAB | 2021/11/18 00:00 | George Mason v Maryland | W | 71-66 |
| NCAAB | 2021/11/14 23:00 | Morgan State v George Mason | W | 53-90 |
| NCAAB | 2021/11/13 00:00 | Pennsylvania v George Mason | W | 66-87 |
| NCAAB | 2021/11/10 00:00 | Stony Brook v George Mason | W | 52-74 |
| NCAAB | 2021/03/05 22:30 | George Mason v Davidson | L | 67-99 |
| NCAAB | 2021/11/24 02:30 | Washington v South Dakota State | L | 87-76 |
| NCAAB | 2021/11/23 00:00 | Nevada v South Dakota State | W | 75-102 |
| NCAAB | 2021/11/19 02:15 | South Dakota State v Presentation College Saints | W | 99-62 |
| NCAAB | 2021/11/18 01:00 | Montana State v South Dakota State | W | 74-91 |
| NCAAB | 2021/11/14 20:00 | South Dakota State v Stephen F Austin | W | 83-71 |
| NCAAB | 2021/11/13 01:00 | South Dakota State v Alabama | L | 88-104 |
| NCAAB | 2021/11/10 02:15 | Bradley v South Dakota State | W | 65-81 |
| NCAAB | 2021/03/08 23:45 | Oral Roberts v South Dakota State | L | 90-88 |