Stadium: Great Southern Bank Arena
Home Manager: Dana Ford Away Manager: Bryan Mullins
| NCAAB | 2021/02/18 02:15 | Missouri State v Southern Illinois | L | 68-53 |
| NCAAB | 2021/02/11 01:00 | Southern Illinois v Missouri State | L | 53-65 |
| NCAAB | 2020/02/29 21:00 | Southern Illinois v Missouri State | L | 59-84 |
| NCAAB | 2020/02/09 01:00 | Missouri State v Southern Illinois | W | 66-68 |
| NCAAB | 2019/02/07 01:00 | Southern Illinois v Missouri State | L | 59-65 |
| NCAAB | 2019/01/03 01:00 | Missouri State v Southern Illinois | W | 70-75 |
| NCAAB | 2018/03/03 00:00 | Missouri State v Southern Illinois | W | 63-67 |
| NCAAB | 2018/02/15 01:00 | Missouri State v Southern Illinois | W | 80-81 |
| NCAAB | 2022/01/09 00:00 | Southern Illinois v Valparaiso | W | 63-60 |
| NCAAB | 2021/12/29 01:00 | Grambling State v Southern Illinois | W | 64-75 |
| NCAAB | 2021/12/22 22:00 | Southern Illinois v San Francisco | L | 52-64 |
| NCAAB | 2021/12/18 21:00 | Southern Illinois v Maryville | W | 75-55 |
| NCAAB | 2021/12/16 01:00 | SE Missouri State v Southern Illinois | W | 55-80 |
| NCAAB | 2021/12/11 19:00 | Southern Illinois v Tulsa | L | 65-69 |
| NCAAB | 2021/12/05 02:00 | Southern Miss v Southern Illinois | W | 41-66 |
| NCAAB | 2021/12/02 00:00 | Southern Illinois v Evansville | W | 54-52 |
| NCAAB | 2022/01/08 23:00 | Northern Iowa v Missouri State | L | 85-84 |
| NCAAB | 2022/01/06 02:00 | Missouri State v Bradley | W | 71-69 |
| NCAAB | 2022/01/03 01:00 | Drake v Missouri State | W | 56-61 |
| NCAAB | 2021/12/30 18:00 | Missouri State v Evangel | W | 103-56 |
| NCAAB | 2021/12/23 03:00 | Missouri State v Saint Mary's CA | L | 58-75 |
| NCAAB | 2021/12/19 01:00 | Central Arkansas v Missouri State | W | 70-106 |
| NCAAB | 2021/12/16 00:00 | South Dakota State v Missouri State | W | 63-75 |
| NCAAB | 2021/12/11 21:00 | Oral Roberts v Missouri State | W | 60-69 |