Stadium: Kirby Sports Center
Home Manager: Fran O'Hanlon Away Manager: Tavaras Hardy
| NCAAB | 2022/01/14 00:00 | Lafayette v Loyola Maryland | W | 60-74 |
| NCAAB | 2021/02/14 22:00 | Lafayette v Loyola Maryland | W | 69-88 |
| NCAAB | 2021/02/13 19:00 | Loyola Maryland v Lafayette | L | 94-97 |
| NCAAB | 2021/02/09 00:00 | Loyola Maryland v Lafayette | L | 76-80 |
| NCAAB | 2021/02/07 17:00 | Lafayette v Loyola Maryland | W | 62-75 |
| NCAAB | 2021/01/17 23:00 | Lafayette v Loyola Maryland | L | 72-70 |
| NCAAB | 2021/01/16 21:00 | Loyola Maryland v Lafayette | L | 75-77 |
| NCAAB | 2020/02/23 19:00 | Loyola Maryland v Lafayette | W | 70-68 |
| NCAAB | 2022/02/12 22:00 | Colgate v Loyola Maryland | L | 64-56 |
| NCAAB | 2022/02/10 00:00 | Loyola Maryland v Holy Cross | L | 64-68 |
| NCAAB | 2022/02/05 22:00 | Navy v Loyola Maryland | L | 56-55 |
| NCAAB | 2022/02/03 00:00 | Army v Loyola Maryland | W | 57-61 |
| NCAAB | 2022/01/30 23:00 | Loyola Maryland v Bucknell | L | 80-82 |
| NCAAB | 2022/01/30 23:00 | Bucknell v Loyola Maryland | L | 82-80 |
| NCAAB | 2022/01/25 00:00 | Loyola Maryland v Colgate | L | 52-65 |
| NCAAB | 2022/01/22 19:00 | American v Loyola Maryland | W | 73-78 |
| NCAAB | 2022/02/14 23:00 | Lafayette v Colgate | L | 61-69 |
| NCAAB | 2022/02/12 17:00 | Lafayette v Lehigh | W | 73-69 |
| NCAAB | 2022/02/08 00:00 | Lafayette v Navy | L | 44-68 |
| NCAAB | 2022/02/05 19:00 | Bucknell v Lafayette | W | 72-74 |
| NCAAB | 2022/02/03 00:00 | American v Lafayette | W | 62-71 |
| NCAAB | 2022/01/31 23:00 | Colgate v Lafayette | L | 72-61 |
| NCAAB | 2022/01/29 18:00 | Lafayette v Army | L | 56-60 |
| NCAAB | 2022/01/27 00:00 | Boston U v Lafayette | L | 81-62 |