Stadium: Thomas Assembly Center
Home Manager: Eric Konkol Away Manager: Johnny Jones
| NCAAB | 2021/11/25 02:00 | Texas Southern v BYU | L | 64-81 |
| NCAAB | 2021/11/21 23:00 | Texas Southern v NC State | L | 57-65 |
| NCAAB | 2021/11/18 02:00 | Texas Southern v Air Force | L | 57-61 |
| NCAAB | 2021/11/16 02:00 | Texas Southern v Washington | L | 65-72 |
| NCAAB | 2021/11/13 03:00 | Texas Southern v Saint Mary's CA | L | 58-67 |
| NCAAB | 2021/11/10 00:00 | Texas Southern v Oregon | L | 66-83 |
| NCAAB | 2021/03/20 19:00 | Texas Southern v Michigan | L | 66-82 |
| NCAAB | 2021/03/18 21:10 | Mount St Marys v Texas Southern | W | 52-60 |
| NCAAB | 2021/11/27 19:00 | Louisiana Tech v NC State | L | 81-90 |
| NCAAB | 2021/11/25 00:30 | UL Monroe v Louisiana Tech | W | 74-96 |
| NCAAB | 2021/11/20 01:30 | Louisiana Tech v Northwestern State | W | 83-64 |
| NCAAB | 2021/11/15 08:27 | Louisiana Tech v Jarvis Christian | W | 91-61 |
| NCAAB | 2021/11/13 00:30 | Jackson State v Louisiana Tech | W | 68-70 |
| NCAAB | 2021/11/10 02:00 | Louisiana Tech v Alabama | L | 64-93 |
| NIT | 2021/03/28 19:00 | Louisiana Tech v Colorado State | W | 76-74 |
| NIT | 2021/03/27 19:00 | Mississippi State v Louisiana Tech | L | 84-62 |