Stadium: Exactech Arena at the Stephen C. O'Connell Center
Home Manager: Mike White Away Manager: Johnny Jones
| NCAAB | 2021/12/02 00:30 | Texas Southern v Louisiana Tech | L | 60-87 |
| NCAAB | 2021/11/25 02:00 | Texas Southern v BYU | L | 64-81 |
| NCAAB | 2021/11/21 23:00 | Texas Southern v NC State | L | 57-65 |
| NCAAB | 2021/11/18 02:00 | Texas Southern v Air Force | L | 57-61 |
| NCAAB | 2021/11/16 02:00 | Texas Southern v Washington | L | 65-72 |
| NCAAB | 2021/11/13 03:00 | Texas Southern v Saint Mary's CA | L | 58-67 |
| NCAAB | 2021/11/10 00:00 | Texas Southern v Oregon | L | 66-83 |
| NCAAB | 2021/03/20 19:00 | Texas Southern v Michigan | L | 66-82 |
| NCAAB | 2021/12/02 01:00 | Florida Gators v Oklahoma | L | 67-74 |
| NCAAB | 2021/11/28 17:00 | Troy v Florida Gators | W | 45-84 |
| NCAAB | 2021/11/25 01:30 | Ohio State v Florida Gators | W | 68-71 |
| NCAAB | 2021/11/23 01:30 | California v Florida Gators | W | 60-80 |
| NCAAB | 2021/11/18 23:00 | Wisc Milwaukee v Florida Gators | W | 45-81 |
| NCAAB | 2021/11/14 18:00 | Florida State v Florida Gators | W | 55-71 |
| NCAAB | 2021/11/10 00:00 | Elon v Florida Gators | W | 61-74 |
| NCAAB | 2021/03/21 23:45 | Oral Roberts v Florida Gators | L | 81-78 |