Stadium: Freedom Hall Civic Center
Home Manager: Desmond Oliver Away Manager: Dave Dickerson
| NCAAB | 2014/02/28 12:00 | USC Upstate v East Tenn St | W | 79-73 |
| NCAAB | 2014/02/10 12:00 | East Tenn St v USC Upstate | W | 63-75 |
| NCAAB | 2013/03/01 12:00 | East Tenn St v USC Upstate | W | 56-88 |
| NCAAB | 2013/01/28 12:00 | USC Upstate v East Tenn St | W | 88-71 |
| NCAAB | 2012/01/27 12:00 | USC Upstate v East Tenn St | W | 58-54 |
| NCAAB | 2012/01/04 12:00 | East Tenn St v USC Upstate | L | 88-73 |
| NCAAB | 2011/01/25 12:00 | East Tenn St v USC Upstate | L | 67-52 |
| NCAAB | 2010/12/05 12:00 | USC Upstate v East Tenn St | W | 60-59 |
| NCAAB | 2021/11/15 23:00 | USC Upstate v St. Andrew's | W | 96-43 |
| NCAAB | 2021/11/13 00:00 | USC Upstate v Charlotte U | L | 64-76 |
| NCAAB | 2021/11/10 00:00 | USC Upstate v SC Gamecocks | L | 60-78 |
| NCAAB | 2021/02/27 21:00 | USC Upstate v High Point | L | 60-65 |
| NCAAB | 2021/02/22 23:00 | Gardner Webb v USC Upstate | L | 69-58 |
| NCAAB | 2021/02/18 22:00 | USC Upstate v Presbyterian | W | 65-51 |
| NCAAB | 2021/02/15 23:00 | USC Upstate v Presbyterian | L | 65-75 |
| NCAAB | 2021/02/13 00:00 | USC Upstate v Campbell | L | 49-64 |
| NCAAB | 2021/11/14 17:00 | East Tenn St v Tennessee | L | 62-94 |
| NCAAB | 2021/11/12 23:30 | East Tenn St v Appalachian State | L | 67-69 |
| NCAAB | 2021/03/07 22:00 | East Tenn St v NC Greensboro | L | 65-77 |
| NCAAB | 2021/03/06 19:30 | East Tenn St v Chattanooga | W | 63-53 |
| NCAAB | 2021/02/27 21:00 | NC Greensboro v East Tenn St | L | 85-74 |
| NCAAB | 2021/02/18 00:00 | Mercer v East Tenn St | L | 71-64 |
| NCAAB | 2021/02/16 00:00 | East Tenn St v Chattanooga | L | 51-53 |
| NCAAB | 2021/02/13 21:00 | Wofford v East Tenn St | W | 49-71 |