Stadium: Colonial Life Arena
Home Manager: Frank Martin Away Manager: Andy Kennedy
| NCAAB | 2021/11/14 20:00 | UAB v Rhodes | W | 98-61 |
| NCAAB | 2021/11/13 00:00 | Morehead State v UAB | W | 71-85 |
| NCAAB | 2021/11/10 00:30 | UNC Asheville v UAB | W | 77-102 |
| NCAAB | 2021/03/12 17:00 | UAB v Western Kentucky | L | 60-64 |
| NCAAB | 2021/03/12 00:00 | Rice v UAB | W | 60-73 |
| NCAAB | 2021/03/06 22:00 | UAB v North Texas | W | 65-61 |
| NCAAB | 2021/03/06 01:00 | UAB v North Texas | W | 65-51 |
| NCAAB | 2021/02/27 21:00 | UAB v Texas San Antonio | L | 79-96 |
| NCAAB | 2021/11/14 22:00 | Western Kentucky v SC Gamecocks | W | 64-75 |
| NCAAB | 2021/11/13 02:00 | Princeton v SC Gamecocks | L | 66-62 |
| NCAAB | 2021/11/10 00:00 | USC Upstate v SC Gamecocks | W | 60-78 |
| NCAAB | 2021/03/12 02:00 | SC Gamecocks v Mississippi | L | 59-76 |
| NCAAB | 2021/03/06 17:00 | SC Gamecocks v Kentucky | L | 64-92 |
| NCAAB | 2021/03/02 23:30 | Arkansas v SC Gamecocks | L | 101-73 |
| NCAAB | 2021/02/27 18:00 | SC Gamecocks v Georgia Bulldogs | W | 91-70 |
| NCAAB | 2021/02/25 00:00 | SC Gamecocks v Mississippi State | L | 48-69 |