Stadium: Jack Breslin Students Events Center
Home Manager: Tom Izzo Away Manager: Chris Collins
| NCAAB | 2022/01/02 19:00 | Michigan State v Northwestern | L | 73-67 |
| NCAAB | 2020/12/21 00:00 | Michigan State v Northwestern | W | 65-79 |
| NCAAB | 2020/01/29 23:30 | Northwestern v Michigan State | L | 50-79 |
| NCAAB | 2019/12/19 01:00 | Michigan State v Northwestern | L | 77-72 |
| NCAAB | 2019/01/03 01:30 | Northwestern v Michigan State | L | 55-81 |
| NCAAB | 2018/02/17 19:00 | Michigan State v Northwestern | L | 65-60 |
| NCAAB | 2016/12/30 23:00 | Northwestern v Michigan State | L | 52-61 |
| NCAAB | 2016/01/29 02:00 | Northwestern v Michigan State | L | 45-76 |
| NCAAB | 2022/01/13 02:00 | Maryland v Northwestern | L | 94-87 |
| NCAAB | 2022/01/09 22:30 | Northwestern v Ohio State | L | 87-95 |
| NCAAB | 2022/01/06 02:00 | Penn State v Northwestern | L | 74-70 |
| NCAAB | 2022/01/02 19:00 | Michigan State v Northwestern | L | 73-67 |
| NCAAB | 2021/12/20 23:00 | Northwestern v Illinois Springfield | W | 90-50 |
| NCAAB | 2021/12/12 21:00 | NJIT v Northwestern | W | 52-70 |
| NCAAB | 2021/12/05 17:00 | Northwestern v Maryland | W | 67-61 |
| NCAAB | 2021/12/01 02:00 | Northwestern v Wake Forest | L | 73-77 |
| NCAAB | 2022/01/13 00:00 | Minnesota v Michigan State | W | 69-71 |
| NCAAB | 2022/01/06 00:00 | Nebraska v Michigan State | W | 67-79 |
| NCAAB | 2022/01/02 19:00 | Michigan State v Northwestern | W | 73-67 |
| NCAAB | 2021/12/29 20:00 | High Point v Michigan State | W | 68-81 |
| NCAAB | 2021/12/22 00:30 | Michigan State v Oakland | W | 90-78 |
| NCAAB | 2021/12/11 19:00 | Penn State v Michigan State | W | 64-80 |
| NCAAB | 2021/12/09 02:00 | Michigan State v Minnesota | W | 75-67 |
| NCAAB | 2021/12/04 22:00 | Toledo v Michigan State | W | 68-81 |