Louisville 64-73 Michigan State 2021-12-02 00:15
Stadium: Jack Breslin Students Events Center
Home Manager: Tom Izzo Away Manager: Chris Mack
Head to Head
| NCAAB | 2018/11/28 00:30 | Michigan State v Louisville | W | 78-82 |
| NCAAB | 2015/12/03 00:15 | Michigan State v Louisville | L | 71-67 |
| NCAAB | 2015/03/29 18:20 | Louisville v Michigan State | L | 70-76 |
Home History
| NCAAB | 2021/11/27 15:00 | Maryland v Louisville | W | 55-63 |
| NCAAB | 2021/11/26 02:30 | Louisville v Mississippi State | W | 72-58 |
| NCAAB | 2021/11/20 19:00 | Detroit v Louisville | W | 67-73 |
| NCAAB | 2021/11/16 01:00 | Navy v Louisville | W | 60-77 |
| NCAAB | 2021/11/13 00:00 | Furman v Louisville | L | 80-72 |
| NCAAB | 2021/11/10 03:00 | Southern v Louisville | W | 60-72 |
| NCAAB | 2021/03/10 23:30 | Duke v Louisville | L | 70-56 |
| NCAAB | 2021/03/06 21:00 | Virginia v Louisville | L | 68-58 |
Away History
| NCAAB | 2021/11/26 16:00 | Baylor Bears v Michigan State | L | 75-58 |
| NCAAB | 2021/11/25 17:00 | Connecticut v Michigan State | W | 60-64 |
| NCAAB | 2021/11/24 15:00 | Loyola Chicago v Michigan State | W | 61-63 |
| NCAAB | 2021/11/20 22:00 | Eastern Michigan v Michigan State | W | 59-83 |
| NCAAB | 2021/11/18 00:00 | Michigan State v Butler | W | 73-52 |
| NCAAB | 2021/11/12 23:30 | Western Michigan v Michigan State | W | 46-90 |
| NCAAB | 2021/11/10 00:00 | Kansas v Michigan State | L | 87-74 |
| NCAAB | 2021/03/19 02:19 | UCLA v Michigan State | L | 86-80 |