Stadium: Littlejohn Coliseum
Home Manager: Brad Brownell Away Manager: Jeff Capel
| NCAAB | 2021/03/06 17:00 | Pittsburgh v Clemson | L | 62-77 |
| NCAAB | 2020/02/13 02:00 | Clemson v Pittsburgh | L | 72-52 |
| NCAAB | 2019/02/28 00:00 | Clemson v Pittsburgh | L | 62-48 |
| NCAAB | 2019/01/30 02:00 | Pittsburgh v Clemson | L | 69-82 |
| NCAAB | 2018/02/09 00:00 | Pittsburgh v Clemson | L | 48-72 |
| NCAAB | 2017/01/28 17:00 | Clemson v Pittsburgh | L | 67-60 |
| NCAAB | 2016/01/28 00:00 | Clemson v Pittsburgh | L | 73-60 |
| NCAAB | 2015/01/10 17:00 | Pittsburgh v Clemson | L | 62-71 |
| NCAAB | 2022/01/20 02:00 | Virginia v Pittsburgh | L | 66-61 |
| NCAAB | 2022/01/15 21:00 | Louisville v Pittsburgh | W | 53-65 |
| NCAAB | 2022/01/12 00:00 | Pittsburgh v Syracuse | L | 61-77 |
| NCAAB | 2022/01/08 21:00 | Boston College v Pittsburgh | W | 67-69 |
| NCAAB | 2022/01/06 00:00 | Pittsburgh v Louisville | L | 72-75 |
| NCAAB | 2021/12/29 01:00 | Notre Dame v Pittsburgh | L | 68-67 |
| NCAAB | 2021/12/21 19:00 | Jacksonville v Pittsburgh | W | 55-64 |
| NCAAB | 2021/12/18 17:00 | Pittsburgh v St Johns | W | 59-57 |
| NCAAB | 2022/01/19 02:00 | Clemson v Syracuse | L | 78-91 |
| NCAAB | 2022/01/15 23:30 | Boston College v Clemson | L | 70-68 |
| NCAAB | 2022/01/13 00:00 | Clemson v Notre Dame | L | 56-72 |
| NCAAB | 2022/01/08 17:00 | Clemson v NC State | W | 70-65 |
| NCAAB | 2022/01/05 02:00 | Virginia v Clemson | L | 75-65 |
| NCAAB | 2021/12/23 00:00 | Clemson v Virginia | W | 67-50 |
| NCAAB | 2021/12/18 23:00 | SC Gamecocks v Clemson | W | 56-70 |
| NCAAB | 2021/12/15 00:00 | Miami Ohio v Clemson | W | 76-89 |